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适度饮酒会损害大脑吗?

Does a "moderate" alcohol intake damage the brain?

作者信息

Harper C, Kril J, Daly J

机构信息

Department of Pathology, University of Sydney, NSW, Australia.

出版信息

J Neurol Neurosurg Psychiatry. 1988 Jul;51(7):909-13. doi: 10.1136/jnnp.51.7.909.

Abstract

A range of volumetric and neurochemical analyses were carried out on the brains of 14 "moderate" drinkers. These data were compared with previous studies from controls and alcoholics. Volumetric measurements consistently suggest a loss of cerebral tissue although the differences were not statistically significant. Changes in the lipid and water content of the white matter were noted and the significance of these changes in relation to the pathogenesis of reversible brain shrinkage caused by alcohol abuse is discussed.

摘要

对14名“适度”饮酒者的大脑进行了一系列体积和神经化学分析。这些数据与之前对照组和酗酒者的研究进行了比较。体积测量结果一致表明存在脑组织损失,尽管差异无统计学意义。注意到白质中脂质和水分含量的变化,并讨论了这些变化与酒精滥用导致的可逆性脑萎缩发病机制的关系。

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J Neurochem. 1962 Jul-Aug;9:427-32. doi: 10.1111/j.1471-4159.1962.tb09470.x.
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Genetic dependence of alcohol-related disease: animal models.酒精相关疾病的遗传依赖性:动物模型
Aust N Z J Med. 1981 Apr;11(2):148-53. doi: 10.1111/j.1445-5994.1981.tb04222.x.
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ABC of alcohol. Definitions.酒精知识ABC。定义。
Br Med J (Clin Res Ed). 1981 Nov 7;283(6301):1248-50. doi: 10.1136/bmj.283.6301.1248.
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Intracranial cavity volumes: a new method and its potential applications.颅内腔体积:一种新方法及其潜在应用。
Neuropathol Appl Neurobiol. 1984 Jan-Feb;10(1):25-32. doi: 10.1111/j.1365-2990.1984.tb00337.x.
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