Harper C, Kril J, Daly J
Department of Pathology, University of Sydney, NSW, Australia.
J Neurol Neurosurg Psychiatry. 1988 Jul;51(7):909-13. doi: 10.1136/jnnp.51.7.909.
A range of volumetric and neurochemical analyses were carried out on the brains of 14 "moderate" drinkers. These data were compared with previous studies from controls and alcoholics. Volumetric measurements consistently suggest a loss of cerebral tissue although the differences were not statistically significant. Changes in the lipid and water content of the white matter were noted and the significance of these changes in relation to the pathogenesis of reversible brain shrinkage caused by alcohol abuse is discussed.
对14名“适度”饮酒者的大脑进行了一系列体积和神经化学分析。这些数据与之前对照组和酗酒者的研究进行了比较。体积测量结果一致表明存在脑组织损失,尽管差异无统计学意义。注意到白质中脂质和水分含量的变化,并讨论了这些变化与酒精滥用导致的可逆性脑萎缩发病机制的关系。