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酒精性脑萎缩并非由水合作用变化引起:一项病理学研究

Brain shrinkage in alcoholics is not caused by changes in hydration: a pathological study.

作者信息

Harper C G, Kril J J, Daly J M

机构信息

Department of Pathology, University of Sydney, Australia.

出版信息

J Neurol Neurosurg Psychiatry. 1988 Jan;51(1):124-7. doi: 10.1136/jnnp.51.1.124.

Abstract

Measurement of the water content of the cerebral white matter in 26 control and 24 alcoholic cases supports in vivo MRI studies and previous necropsy studies which appeared to show an increase in the water content in the alcoholic group. This negates the hypothesis that reversible brain shrinkage in alcoholics is caused by changes in the state of hydration.

摘要

对26名对照者和24名酗酒者的脑白质含水量进行测量,这一结果支持了活体磁共振成像研究以及之前的尸检研究,这些研究似乎表明酗酒者组的含水量有所增加。这否定了酗酒者可逆性脑萎缩是由水合状态变化引起的这一假设。

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本文引用的文献

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Cerebral lipids in multiple sclerosis.多发性硬化症中的脑脂质
J Neurochem. 1962 Jul-Aug;9:427-32. doi: 10.1111/j.1471-4159.1962.tb09470.x.
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Brain electrolytes in depressive and alcoholic suicides.抑郁和酒精所致自杀者的脑电解质
Br J Psychiatry. 1969 Jan;115(518):69-79. doi: 10.1192/bjp.115.518.69.
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Electrolyte content of the brain in alcoholism.
Br J Psychiatry. 1970 Feb;116(531):185-93. doi: 10.1192/bjp.116.531.185.
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J Neurol Neurosurg Psychiatry. 1985 Jan;48(1):21-8. doi: 10.1136/jnnp.48.1.21.
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