Isolation and characterization of catalase deficient mutants of Salmonella typhimurium.

Catalase deficient mutants (kat) of Salmonella typhimurium have been isolated. The mutantions katA1, katC6 and katD9 appear to map at about minute 10 on the Salmonella chromosome. The katC6 and katD9 lesions are complemented by the E. coli F'128 (lac + pro +) episome but the katA1 lesion is not. KatB2 maps at about minute 100. None of the mutants are oxygen sensitive; they grow as well as wild bacteria, even when aerated.