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人工关节周围感染的间隔设计选择与考虑因素。

Spacer Design Options and Consideration for Periprosthetic Joint Infection.

机构信息

RUSH University Medical Center, Chicago, IL.

出版信息

J Arthroplasty. 2020 Mar;35(3S):S31-S34. doi: 10.1016/j.arth.2019.11.007.

Abstract

An articulating or nonarticulating antibiotic hip spacer can be placed following the first stage implant removal of a periprosthetic hip joint infection. Antibiotic spacers help fill in the dead space created at the time of resection and provide a high local concentration of antibiotics. Theoretical advantages of a static spacer include a higher elution of antibiotics because of the increased surface area, the ability to protect deficient bone in the proximal femur/acetabulum, and the ability to immobilize the periarticular soft tissues. Advantages of an articulating spacer include improved ambulation and easier motion for the patient, maintenance of soft tissue tension, and an easier surgical reconstruction at the time of the second stage. Additionally, an articulating antibiotic spacer may minimize the risk of dislocation following the second stage reconstruction. The choice of articulating or nonarticulating is currently one of surgeon preference yet it is advised that surgeons consider an articulating spacer for all patients except those with severe femoral/acetabular bone loss or deficient abductors.

摘要

在初次阶段的髋关节假体周围感染清创翻修术中,可以在取出一期植入物后,留置活动或非活动抗生素骨水泥间隔器。抗生素间隔器有助于填补切除时产生的死腔,并提供高浓度的局部抗生素。静态间隔器的理论优势包括:由于表面积增加,抗生素洗脱率更高,保护股骨近端/髋臼处的骨量不足,以及固定关节周围软组织的能力。活动间隔器的优势包括改善患者的活动能力,便于患者活动,保持软组织张力,以及在二期手术时更容易进行重建。此外,二期重建后使用活动抗生素间隔器可能会降低脱位的风险。目前,选择活动或非活动间隔器取决于外科医生的偏好,但建议外科医生除了那些有严重的股骨/髋臼骨量丢失或外展肌无力的患者外,应为所有患者考虑使用活动抗生素间隔器。

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