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视网膜色素上皮撕裂。

Retinal Pigment Epithelium Tear.

作者信息

Rachitskaya Aleksandra V, Goldhardt Raquel

机构信息

Cleveland Clinic Cole Eye Institute, 9500 Euclid Avenue / i32, Cleveland, OH 44195.

Bascom Palmer Eye Institute, University of Miami, 900 NW 17th Street, Miami, FL 33136.

出版信息

Curr Ophthalmol Rep. 2015 Mar;3(1):26-33. doi: 10.1007/s40135-014-0057-1. Epub 2014 Dec 6.

DOI:10.1007/s40135-014-0057-1
PMID:32051789
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7015457/
Abstract

Retinal pigment epithelium tear is a potentially vision threatening complication of retinal pigment epithelial detachment associated with neovascular age-related macular degeneration. Retinal pigment epithelium tear has been reported to occur spontaneously and after treatment with anti-vascular growth endothelial factor agents. The current study summarizes the presentation, diagnosis, management, and outcomes of retinal pigment epithelium tears.

摘要

视网膜色素上皮撕裂是与新生血管性年龄相关性黄斑变性相关的视网膜色素上皮脱离的一种潜在威胁视力的并发症。据报道，视网膜色素上皮撕裂可自发发生，也可在使用抗血管生成内皮因子药物治疗后出现。本研究总结了视网膜色素上皮撕裂的临床表现、诊断、治疗及预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/402d/7015457/4437c015d7d1/nihms-1055539-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/402d/7015457/31b3e75b7d8e/nihms-1055539-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/402d/7015457/7b3a810aca21/nihms-1055539-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/402d/7015457/4437c015d7d1/nihms-1055539-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/402d/7015457/31b3e75b7d8e/nihms-1055539-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/402d/7015457/7b3a810aca21/nihms-1055539-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/402d/7015457/4437c015d7d1/nihms-1055539-f0003.jpg

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本文引用的文献

1
Repair mechanism of retinal pigment epithelial tears in age-related macular degeneration.年龄相关性黄斑变性中视网膜色素上皮撕裂的修复机制
Retina. 2015 Mar;35(3):473-80. doi: 10.1097/IAE.0000000000000337.
2
Fundus autofluorescence in patients with retinal pigment epithelial (RPE) tears: an in-vivo evaluation of RPE resurfacing.视网膜色素上皮（RPE）撕裂患者的眼底自发荧光：RPE 再上皮化的体内评估
Graefes Arch Clin Exp Ophthalmol. 2014 Jul;252(7):1059-63. doi: 10.1007/s00417-013-2549-3. Epub 2014 Jan 10.
3
Pigment epithelial tears associated with anti-VEGF therapy: incidence, long-term visual outcome, and relationship with pigment epithelial detachment in age-related macular degeneration.
新生血管性年龄相关性黄斑变性中的光学相干断层扫描生物标志物：一项叙述性综述。
J Ophthalmol. 2021 Jul 17;2021:9994098. doi: 10.1155/2021/9994098. eCollection 2021.
抗VEGF治疗相关的色素上皮撕裂：年龄相关性黄斑变性中的发生率、长期视力转归及其与色素上皮脱离的关系
Retina. 2014 Jun;34(6):1156-62. doi: 10.1097/IAE.0000000000000056.
4
Higher incidence of retinal pigment epithelium tears after ranibizumab in neovascular age-related macular degeneration with increasing pigment epithelium detachment height.在新生血管性年龄相关性黄斑变性中，随着色素上皮脱离高度增加，雷珠单抗治疗后视网膜色素上皮撕裂的发生率更高。
Br J Ophthalmol. 2013 Nov;97(11):1486-7. doi: 10.1136/bjophthalmol-2013-303978. Epub 2013 Sep 13.
5
Mechanism of retinal pigment epithelium tear formation following intravitreal anti-vascular endothelial growth factor therapy revealed by spectral-domain optical coherence tomography.频域光相干断层扫描揭示玻璃体内抗血管内皮生长因子治疗后视网膜色素上皮撕裂的形成机制。
Am J Ophthalmol. 2013 Nov;156(5):981-988.e2. doi: 10.1016/j.ajo.2013.06.024. Epub 2013 Aug 20.
6
Additional anti-vascular endothelial growth factor therapy for eyes with a retinal pigment epithelial tear after the initial therapy.初始治疗后针对伴有视网膜色素上皮撕裂的眼睛的额外抗血管内皮生长因子治疗。
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Retinal pigment epithelium tear after intravitreal aflibercept injection.玻璃体内注射阿柏西普后视网膜色素上皮撕裂
Clin Ophthalmol. 2013;7:1287-9. doi: 10.2147/OPTH.S47735. Epub 2013 Jun 26.
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Can J Ophthalmol. 2013 Jun;48(3):210-5. doi: 10.1016/j.jcjo.2013.01.023.
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Prospective evaluation of the incidence and risk factors for the development of RPE tears after high- and low-dose ranibizumab therapy.前瞻性评估高、低剂量雷珠单抗治疗后 RPE 撕裂的发生率及相关风险因素。
Retina. 2013 Sep;33(8):1551-7. doi: 10.1097/IAE.0b013e31828992f5.