新型冠状病毒肺炎（2019-nCoV）患者的初始 CT 表现及时间演变：中国武汉 63 例患者研究。
Initial CT findings and temporal changes in patients with the novel coronavirus pneumonia (2019-nCoV): a study of 63 patients in Wuhan, China.
机构信息
Department of radiology, Tongji hospital, Huazhong University of Science and Technology, Wuhan, 430030, People's Republic of China.
出版信息
Eur Radiol. 2020 Jun;30(6):3306-3309. doi: 10.1007/s00330-020-06731-x. Epub 2020 Feb 13.
OBJECTIVES
The purpose of this study was to observe the imaging characteristics of the novel coronavirus pneumonia.
METHODS
Sixty-three confirmed patients were enrolled from December 30, 2019 to January 31, 2020. High-resolution CT (HRCT) of the chest was performed. The number of affected lobes, ground glass nodules (GGO), patchy/punctate ground glass opacities, patchy consolidation, fibrous stripes and irregular solid nodules in each patient's chest CT image were recorded. Additionally, we performed imaging follow-up of these patients.
RESULTS
CT images of 63 confirmed patients were collected. M/F ratio: 33/30. The mean age was 44.9 ± 15.2 years. The mean number of affected lobes was 3.3 ± 1.8. Nineteen (30.2%) patients had one affected lobe, five (7.9%) patients had two affected lobes, four (6.3%) patients had three affected lobes, seven (11.1%) patients had four affected lobes while 28 (44.4%) patients had 5 affected lobes. Fifty-four (85.7%) patients had patchy/punctate ground glass opacities, 14 (22.2%) patients had GGO, 12 (19.0%) patients had patchy consolidation, 11 (17.5%) patients had fibrous stripes and 8 (12.7%) patients had irregular solid nodules. Fifty-four (85.7%) patients progressed, including single GGO increased, enlarged and consolidated; fibrous stripe enlarged, while solid nodules increased and enlarged.
CONCLUSIONS
Imaging changes in novel viral pneumonia are rapid. The manifestations of the novel coronavirus pneumonia are diverse. Imaging changes of typical viral pneumonia and some specific imaging features were observed. Therefore, we need to strengthen the recognition of image changes to help clinicians to diagnose quickly and accurately.
KEY POINTS
• High-resolution CT (HRCT) of the chest is critical for early detection, evaluation of disease severity and follow-up of patients with the novel coronavirus pneumonia. • The manifestations of the novel coronavirus pneumonia are diverse and change rapidly. • Radiologists should be aware of the various features of the disease and temporal changes.
目的
本研究旨在观察新型冠状病毒肺炎的影像学特征。
方法
纳入 2019 年 12 月 30 日至 2020 年 1 月 31 日期间确诊的 63 例患者。对所有患者行胸部高分辨率 CT（HRCT）检查。记录每位患者胸部 CT 图像中受累肺叶数、磨玻璃结节（GGO）、斑片状/点状磨玻璃影、斑片状实变、纤维条带和不规则实性结节的数量。此外，对这些患者进行了影像学随访。
结果
共采集 63 例确诊患者的 CT 图像。男/女比例为 33/30。平均年龄为 44.9±15.2 岁。平均受累肺叶数为 3.3±1.8。19 例（30.2%）患者为单肺叶受累，5 例（7.9%）患者为双肺叶受累，4 例（6.3%）患者为三肺叶受累，7 例（11.1%）患者为四肺叶受累，28 例（44.4%）患者为五肺叶受累。54 例（85.7%）患者表现为斑片状/点状磨玻璃影，14 例（22.2%）患者表现为 GGO，12 例（19.0%）患者表现为斑片状实变，11 例（17.5%）患者表现为纤维条带，8 例（12.7%）患者表现为不规则实性结节。54 例（85.7%）患者病情进展，表现为单发 GGO 增加、扩大并实变；纤维条带扩大，而实性结节增加、扩大。
结论
新型病毒性肺炎的影像学变化迅速。新型冠状病毒肺炎的表现多样。观察到典型病毒性肺炎的影像学变化和一些特定的影像学特征。因此，我们需要加强对图像变化的认识，以帮助临床医生快速准确地诊断。
关键点
胸部高分辨率 CT（HRCT）对新型冠状病毒肺炎的早期发现、严重程度评估和患者随访至关重要。
新型冠状病毒肺炎的表现多样，变化迅速。
放射科医生应了解该病的各种特征和时间变化。
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