Department of Radiology, First Affiliated Hospital to Army Medical University, Chongqing, China.
Department of Radiology, Three Gorges Central Hospital, Chongqing, China.
J Transl Med. 2020 Apr 6;18(1):154. doi: 10.1186/s12967-020-02324-w.
Since the first case of a coronavirus disease 2019 (COVID-19) infection pneumonia was detected in Wuhan, China, a series of confirmed cases of the COVID-19 were found in Southwest China. The aim of this study was to describe the imaging manifestations of hospitalized patients with confirmed COVID-19 infection in southwest China.
In this retrospective study, data were collected from 131 patients with confirmed coronavirus disease 2019 (COVID-19) from 3 Chinese hospitals. Their common clinical manifestations, as well as characteristics and evolvement features of chest CT images, were analyzed.
A total of 100 (76%) patients had a history of close contact with people living in Wuhan, Hubei. The clinical manifestations of COVID-19 included cough, fever. Most of the lesions identified in chest CT images were multiple lesions of bilateral lungs, lesions were more localized in the peripheral lung, 109 (83%) patients had more than two lobes involved, 20 (15%) patients presented with patchy ground glass opacities, patchy ground glass opacities and consolidation of lesions co-existing in 61 (47%) cases. Complications such as pleural thickening, hydrothorax, pericardial effusion, and enlarged mediastinal lymph nodes were detected but only in rare cases. For the follow-up chest CT examinations (91 cases), We found 66 (73%) cases changed very quickly, with an average of 3.5 days, 25 cases (27%) presented absorbed lesions, progression was observed in 41 cases (46%), 25 (27%) cases showed no significant changes.
Chest CT plays an important role in diagnosing COVID-19. The imaging pattern of multifocal peripheral ground glass or mixed consolidation is highly suspicious of COVID-19, that can quickly change over a short period of time.
自中国武汉首例 2019 年冠状病毒病(COVID-19)感染性肺炎确诊以来,中国西南地区陆续发现多例 COVID-19 确诊病例。本研究旨在描述中国西南地区住院确诊 COVID-19 感染患者的影像学表现。
在这项回顾性研究中,我们从中国 3 家医院的 131 例确诊的新型冠状病毒病(COVID-19)患者中收集了数据。分析了他们常见的临床表现以及胸部 CT 图像的特征和演变特征。
共有 100 例(76%)患者有与居住在湖北武汉的人密切接触史。COVID-19 的临床表现包括咳嗽、发热。胸部 CT 图像上发现的病变多为双侧肺部多发病变,病变更局限于外周肺,109 例(83%)患者有两个以上肺叶受累,20 例(15%)患者呈斑片状磨玻璃影,61 例(47%)患者斑片状磨玻璃影和实变病变并存。仅在少数情况下发现胸膜增厚、胸腔积液、心包积液和纵隔淋巴结肿大等并发症。对 91 例患者进行了随访胸部 CT 检查,我们发现 66 例(73%)患者变化非常迅速,平均 3.5 天,25 例(27%)患者病变吸收,41 例(46%)患者病情进展,25 例(27%)患者无明显变化。
胸部 CT 对诊断 COVID-19 具有重要作用。多灶性外周磨玻璃影或混合实变影的影像学表现高度提示 COVID-19,且在短时间内可迅速变化。