Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran; Department of Pharmaceutical Biotechnology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
Department of Pharmaceutical Nanotechnology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran; Cellular and Molecular Research Center, Cellular and Molecular Medicine Institute, Urmia University of Medical Sciences , Urmia , Iran.
Biosens Bioelectron. 2020 Apr 1;153:112054. doi: 10.1016/j.bios.2020.112054. Epub 2020 Jan 28.
Hybrid silica-gold based sensors show attractive performance in sensing technologies. Due to their interesting optical properties and biological compatibility, gold nanoparticles (AuNPs) have been extensively implemented in sensing technology. Hybridization of AuNPs with silica NPs as a material with unique characteristic comprising large surface area, narrow pore distribution, tunable pore size and excellent charge transport provides great opportunity to fabricate promising sensing materials. This review summarizes the current developments on sensing devices based on gold-silica hybrid materials and discussing their interest in designing biosensors for improved analytes detection.
基于杂化二氧化硅-金的传感器在传感技术中表现出了诱人的性能。由于其有趣的光学性质和生物相容性,金纳米粒子(AuNPs)已广泛应用于传感技术中。将 AuNPs 与二氧化硅 NPs 杂化作为一种具有独特特性的材料,其具有大的表面积、窄的孔径分布、可调的孔径大小和优异的电荷输运性能,为制备有前途的传感材料提供了巨大的机会。本综述总结了基于金-硅杂化材料的传感器件的最新进展,并讨论了它们在设计用于提高分析物检测的生物传感器方面的应用前景。