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[电风暴:识别与管理]

[Electrical storm : Recognition and management].

作者信息

Zarse Markus, Hasan Fuad, Khan Atisha, Karosiene Zana, Lemke Bernd, Bogossian Harilaos

机构信息

Klinikum Lüdenscheid, Klinik für Kardiologie, Elektrophysiologie und Angiologie, Märkische Kliniken GmbH, Paulmannshöherstraße 10-14, 58515, Lüdenscheid, Deutschland.

Universität Witten Herdecke, Alfred-Herrhausen-Straße 50, 58455, Witten, Deutschland.

出版信息

Herzschrittmacherther Elektrophysiol. 2020 Mar;31(1):55-63. doi: 10.1007/s00399-020-00672-0. Epub 2020 Feb 14.

DOI:10.1007/s00399-020-00672-0
PMID:32060611
Abstract

The electrical storm (ES) defined as ≥3 sustained episodes of ventricular tachycardia within a 24 h period comprises a wide spectrum of clinical entities. Mostly patients suffer from severe heart insufficiency and comorbidities making an immediate transfer into a heart center with multidisciplinary expertise in the treatment of ES mandatory. As these patients are often traumatized by ongoing tachycardia despite multiple cardioversions, early deep sedation and β‑blockade to break the vicious circle of sympathico-adrenergic hyperactivation is very effective. Multiple ICD discharges suggesting the diagnosis of ES are inadequate in one third of cases. Pharmacological suppression, frequency control or ablation of supraventricular tachycardias (SVT) help in most cases. In some cases "oversensing" demands optimization of ICD programming. Even so not all adequate ICD discharges, however, are necessary. Since every ICD discharge worsens the patient's prognosis, any kind of ICD discharge should be prevented as far as hemodynamically feasible. After clinical stabilization of the patient with simultaneous acquisition of ECG and testing for reversible causes of ES, ES should be terminated by external or internal cardioversion followed by urgent but elective therapy. Some cases of ES, however, may require immediate escalation of therapy with emergency ablation or revascularization sometimes with circulatory support systems. If ES still persists, a further step in escalation may be taken by cardiac sympathetic denervation. Due to the poor prognosis of patients after ES, close monitoring of the patient, preferably with telemedicine, is indicated.

摘要

电风暴(ES)定义为24小时内出现≥3次持续性室性心动过速发作,涵盖了广泛的临床情况。大多数患者患有严重的心功能不全和合并症,因此必须立即转至具备ES治疗多学科专业知识的心脏中心。由于这些患者尽管多次进行心脏复律仍常因持续性心动过速而受到创伤,早期深度镇静和β受体阻滞剂以打破交感 - 肾上腺素能过度激活的恶性循环非常有效。三分之一的病例中,多次植入式心律转复除颤器(ICD)放电提示ES诊断并不充分。在大多数情况下,药物抑制、频率控制或室上性心动过速(SVT)消融治疗会有所帮助。在某些情况下,“感知过度”需要优化ICD编程。即便如此,并非所有适当的ICD放电都是必要的。由于每次ICD放电都会恶化患者的预后,因此在血流动力学可行的情况下应尽可能预防任何形式的ICD放电。在患者临床稳定的同时采集心电图并检测ES的可逆原因后,应通过体外或体内心脏复律终止ES,随后进行紧急但择期的治疗。然而,一些ES病例可能需要立即升级治疗,进行紧急消融或血管重建,有时还需要循环支持系统。如果ES仍然持续,可通过心脏交感神经切除术进一步升级治疗。鉴于ES后患者预后较差,建议对患者进行密切监测,最好采用远程医疗。

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