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[运动与癌症:治疗期间及治疗后的疗效证据]

[Exercise and cancer: Evidence of efficacy during and after treatments].

作者信息

Ninot Grégory, Flori Nicolas, Huteau Marie-Eve, Stoebner-Delbarre Anne, Senesse Pierre

机构信息

Université de Montpellier, plateforme CEPS, équipe EA4556 Epsylon, Montpellier, France; Institut du Cancer de Montpellier (ICM), département des soins de support, Montpellier, France.

Institut du Cancer de Montpellier (ICM), département des soins de support, Montpellier, France.

出版信息

Bull Cancer. 2020 Apr;107(4):474-489. doi: 10.1016/j.bulcan.2019.11.017. Epub 2020 Feb 12.

DOI:10.1016/j.bulcan.2019.11.017
PMID:32061378
Abstract

After a brief semantic and historical presentation, the article presents the main trials and systematic reviews on the tertiary prevention and care of cancers through physical activity. It gives the keys to understanding how, in forty years of research, interventions dedicated to prevent physical inactivity to reduce the risk of cancer have become as indispensable as adapted physical activity (APA) programs for care pathways. If the public health message "move more" with or without cancer remains true, the research encourages practitioners to implement personalized programs in primary prevention, in addition to treatment and prevention of recurrence. As soon as the diagnosis is made, APA programs will become truly supportive care complementary of treatments, in other words non-pharmacological interventions (NPIs), with the aim of improving the quality of life of patients, improving their overall health, reducing side effects of treatment, potentiate the effects of certain treatments, and reduce the risk of recurrence. Research remains to be carried out notably on the survival, on the advanced cancers and on the integrative modelling of the mechanisms involved.

摘要

在进行了简短的语义和历史介绍之后,本文介绍了通过体育活动对癌症进行三级预防和护理的主要试验和系统评价。它给出了理解以下内容的关键:在四十年的研究中,致力于预防身体不活动以降低癌症风险的干预措施如何变得与适用于护理途径的适应性体育活动(APA)计划一样不可或缺。如果“多运动”这一公共卫生信息无论对有无癌症的人都适用,那么该研究鼓励从业者除了进行治疗和预防复发外,在一级预防中实施个性化计划。一旦做出诊断,APA计划将成为真正支持治疗的补充护理,换句话说就是非药物干预(NPIs),目的是提高患者的生活质量,改善他们的整体健康状况,减少治疗的副作用,增强某些治疗的效果,并降低复发风险。尤其在生存率、晚期癌症以及所涉及机制的综合建模方面仍有待开展研究。

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