Key Laboratory for Integrated Regulation and Resources Development on Shallow Lakes of Ministry of Education, College of Environment, Hohai University, Nanjing 210098, China.
Key Laboratory for Integrated Regulation and Resources Development on Shallow Lakes of Ministry of Education, College of Environment, Hohai University, Nanjing 210098, China; Water Conservancy Project & Civil Engineering College, Tibet Agriculture & Animal Husbandry University, Linzhi 860000, China.
J Hazard Mater. 2020 Jun 5;391:122245. doi: 10.1016/j.jhazmat.2020.122245. Epub 2020 Feb 5.
Little information is available on the bioaccumulation and trophic transfer of pharmaceuticals and personal care products (PPCPs) in urban rivers system, particularly for those affected by water transfer. Herein, a comprehensive study was conducted to investigate the biological residues, bioaccumulation and trophic transfer of 45 PPCPs in the Nanjing Qinhuai River system under the background of water diversion projects. A total of 30 compounds were detected with a descending order of overall concentration as plankton > benthic mollusc > fish (except grass carp). Higher biological residues were observed in the downstream than those in the upstream, with the largest increase for fish (136.4 %) and the lowest increase for phytoplankton (5.4 %). However, the bioaccumulation classifications of most PPCPs were unchanged among the three different water-diversion regions. Trophic magnification factors (TMFs) of organic UV filters (homosalate, oxybenzone, ethylhexyl methoxycinnamate and octocrylene) ranged from 1.23 to 2.04, suggesting trophic magnification potential, while trophic dilution for pharmaceuticals (sertraline, citalopram, caffeine and roxithromycin) with TMFs of 0.42 to 0.50 were observed. A notable positive correlation was observed between the pH-dependent distribution coefficient (logDow) and the TMFs of the PPCPs (P < 0.05). Although the human health hazard assessment indicated no immediate health risk via the consumption of freshwater food, attention should be paid to the joint effects of PPCPs.
有关医药和个人护理产品（PPCPs）在城市河流系统中的生物积累和营养转移的信息很少，特别是对于那些受到调水影响的河流系统。在此背景下，本研究对南水北调工程影响下的南京秦淮河系统中 45 种 PPCPs 的生物残留、生物积累和营养转移进行了全面研究。共检测到 30 种化合物，其总浓度顺序为浮游生物>底栖软体动物>鱼类（草鱼除外）。与上游相比，下游的生物残留量更高，其中鱼类的增加幅度最大（136.4%），浮游生物的增加幅度最小（5.4%）。然而，大多数 PPCPs 的生物积累分类在三个不同的调水区之间没有变化。有机紫外滤光剂（水杨酸甲酯、氧苯酮、乙基己基甲氧基肉桂酸酯和奥克立林）的营养放大因子（TMFs）范围为 1.23 至 2.04，表明具有营养放大潜力，而 TMFs 为 0.42 至 0.50 的药物（舍曲林、西酞普兰、咖啡因和罗红霉素）则表现出营养稀释。PPCPs 的 pH 依赖性分配系数（logDow）与 TMFs 之间存在显著的正相关关系（P<0.05）。尽管通过食用淡水食物进行的人体健康危害评估表明不存在直接健康风险，但仍应注意 PPCPs 的联合效应。
