与单纯血液透析和单纯腹膜透析相比，腹膜透析和血液透析联合治疗的健康相关生活质量：一项横断面研究。

Health-related quality of life on combination therapy with peritoneal dialysis and hemodialysis in comparison with hemodialysis and peritoneal dialysis: A cross-sectional study.

机构信息

Division of Nephrology and Endocrinology, 38551The University of Tokyo School of Medicine, Japan.

Division of Nephrology, Department of Medicine, Japanese Red Cross Medical Center, Tokyo, Japan.

出版信息

Perit Dial Int. 2020 Sep;40(5):462-469. doi: 10.1177/0896860819894066. Epub 2020 Jan 17.

DOI:10.1177/0896860819894066

PMID:32063200

Abstract

BACKGROUND

The health-related quality of life (HRQOL) of dialysis patients has not been well examined, especially in combination therapy with peritoneal dialysis and hemodialysis (PD+HD) patients. We compared the HRQOL of PD+HD patients with that of HD and PD patients.

METHODS

A multicenter, cross-sectional study was conducted on 36 PD+HD, 103 HD, and 90 PD patients in Japan who completed the Kidney Disease Quality of Life Short Form 36, version 1.3. HRQOL scores were summarized into physical- (PCS), mental- (MCS), role/social- (RCS), and kidney disease component summaries (KDCS).

RESULTS

Of the PD+HD patients, 31 (86%) transferred from PD and 5 (14%) transferred from HD. They had the longest dialysis vintage and the smallest urine volume. PCS, MCS, and KDCS HRQOL scores of PD+HD patients were comparable with those of HD and PD patients. However, the RCS score for PD+HD was significantly higher than that for HD ( = 0.020) and comparable with that for PD. PD+HD and PD were associated with significantly higher RCS scores than HD after adjusting for age, gender, diabetic nephropathy, dialysis vintage, ischemic heart disease, and peripheral arterial disease.

CONCLUSIONS

For RCS, HRQOL in PD+HD patients was better than that in HD and comparable with that in PD patients, whereas the PCS, MCS, and KDCS HRQOL scores of PD+HD patients were comparable with those of HD and PD patients.

摘要

背景

透析患者的健康相关生活质量（HRQOL）尚未得到充分研究，尤其是在腹膜透析和血液透析（PD+HD）联合治疗的患者中。我们比较了 PD+HD 患者与 HD 和 PD 患者的 HRQOL。

方法

在日本进行了一项多中心、横断面研究，纳入了 36 名 PD+HD、103 名 HD 和 90 名 PD 患者，他们完成了肾脏病生活质量简表 36 项，版本 1.3。HRQOL 评分总结为生理成分（PCS）、心理成分（MCS）、角色/社会成分（RCS）和肾脏病成分摘要（KDCS）。

结果

PD+HD 患者中，31 名（86%）由 PD 转来，5 名（14%）由 HD 转来。他们的透析时间最长，尿量最小。PD+HD 患者的 PCS、MCS 和 KDCS HRQOL 评分与 HD 和 PD 患者相当。然而，PD+HD 的 RCS 评分显著高于 HD（=0.020），与 PD 相当。调整年龄、性别、糖尿病肾病、透析时间、缺血性心脏病和外周动脉疾病后，PD+HD 和 PD 与 RCS 评分显著升高相关，而 HD 则无此关联。