School of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou Xueyuan Road, Wenzhou, 325102, Zhejiang, China.
Key Laboratory of Vision Science, Ministry of Health, Wenzhou, Zhejiang, China.
Graefes Arch Clin Exp Ophthalmol. 2020 May;258(5):1123-1131. doi: 10.1007/s00417-020-04617-8. Epub 2020 Feb 17.
To compare the accuracy of the eight formulas for intraocular lens (IOL) power calculation in pediatric cataract patients.
A retrospective study. A total of 68 eyes (68 patients) that underwent uneventful cataract surgery and posterior chamber IOL implantation in the capsular bag were enrolled. We compared the calculation accuracy of the 8 formulas at 1 month postoperatively and performed subgroup analysis according to age or axial length (AL).
The mean age at surgery was 34.07 ± 24.60 months and mean AL was 21.12 ± 1.42 mm. The mean prediction errors (PE) of eight formulas for all patients were as follows: SRK II (- 0.66), SRK/T (- 0.44), Holladay 1 (- 0.36), Hoffer Q (- 0.09), Olsen (0.71), Barrett (0.37), Holladay 2 (- 0.70), and Haigis (0.50). There was significant difference among the 8 formulas (p < 0.0001), while no significant difference of absolute PE was found among the 8 formulas in all patients (p = 0.053). Moreover, in patients younger than 2 years old or with AL ≤ 21 mm, SRK/T formula was relatively accurate in 34% and 39% of eyes, respectively. While in patients older than 2 or with AL > 21 mm, Barrett and Haigis formulas were better (58% and 47% for Barrett, 52% and 53% for Haigis).
Overall, in patients younger than 2 years old or with AL ≤ 21 mm, SRK/T formulas were relatively accurate, while Barrett and Haigis formulas were better in patients older than 2 or with AL > 21 mm.
比较 8 种公式在儿童白内障患者人工晶状体(IOL)屈光力计算中的准确性。
回顾性研究。共纳入 68 只眼(68 例),均行白内障超声乳化吸除联合后房型囊袋内 IOL 植入术,术后 1 个月比较 8 种公式的计算准确性,并根据年龄或眼轴(AL)进行亚组分析。
手术时的平均年龄为 34.07±24.60 个月,平均 AL 为 21.12±1.42mm。所有患者 8 种公式的平均预测误差(PE)如下:SRK II(-0.66)、SRK/T(-0.44)、Holladay 1(-0.36)、Hoffer Q(-0.09)、Olsen(0.71)、Barrett(0.37)、Holladay 2(-0.70)和 Haigis(0.50)。8 种公式之间差异有统计学意义(p<0.0001),但所有患者的 8 种公式的绝对 PE 差异无统计学意义(p=0.053)。此外,在年龄小于 2 岁或 AL≤21mm 的患者中,SRK/T 公式在 34%和 39%的眼中相对准确,而在年龄大于 2 岁或 AL>21mm 的患者中,Barrett 和 Haigis 公式更好(Barrett 为 58%和 52%,Haigis 为 53%和 52%)。
总体而言,在年龄小于 2 岁或 AL≤21mm 的患者中,SRK/T 公式相对准确,而在年龄大于 2 岁或 AL>21mm 的患者中,Barrett 和 Haigis 公式更好。