National Referral Unit for Tropical Diseases, Infectious Diseases Department, Ramón y Cajal University Hospital, IRYCIS, Ctra Colmenar, Km 9,100, 28034, Madrid, Spain.
Future Microbiol. 2020 Feb;15:213-225. doi: 10.2217/fmb-2019-0212. Epub 2020 Feb 17.
Globalization has contributed to the emergence of specific parasitic diseases in novel geographical areas, and in these regions, these infections in travelers and immigrants may cause a considerable burden of disease. Timely diagnosis and treatment of protozoan infections to decrease mortality and prevent associated complications are essential. In this respect, the increased availability of specific DNA-detection procedures has improved the diagnosis of many imported parasitic infections. Travelers and immigrants with associated comorbidities or immunosuppression may pose a special challenge regarding management. An updated review of the main protozoan infections in mobile populations (malaria, Chagas disease, leishmaniasis, enteric protozoan infections) is provided, focusing on the changing epidemiology of these diseases, recent developments in diagnosis and management and the possibility of local transmission of imported infections.
全球化导致了一些特定寄生虫病在新的地理区域出现，在这些地区，旅行者和移民中的这些感染可能会导致相当大的疾病负担。及时诊断和治疗原生动物感染以降低死亡率并预防相关并发症至关重要。在这方面，特定 DNA 检测程序的可用性增加提高了许多输入性寄生虫感染的诊断水平。对于合并症或免疫抑制的旅行者和移民，其管理可能会带来特殊挑战。本文就流动人口中主要原生动物感染（疟疾、恰加斯病、利什曼病、肠道原生动物感染）进行了综述，重点关注这些疾病的流行病学变化、近期诊断和管理方面的进展，以及输入性感染的本地传播的可能性。
