Gai Panpan, Yu Wen, Zhao Hao, Qi Ruilian, Li Feng, Liu Libing, Lv Fengting, Wang Shu
Beijing National Laboratory for Molecular Sciences, Key Laboratory of Organic Solids, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
College of Chemistry and Pharmaceutical Sciences, Qingdao Agricultural University, Qingdao, 266109, P. R. China.
Angew Chem Int Ed Engl. 2020 Apr 27;59(18):7224-7229. doi: 10.1002/anie.202001047. Epub 2020 Mar 9.
An organic semiconductor-bacteria biohybrid photosynthetic system is used to efficiently realize CO reduction to produce acetic acid with the non-photosynthetic bacteria Moorella thermoacetica. Perylene diimide derivative (PDI) and poly(fluorene-co-phenylene) (PFP) were coated on the bacteria surface as photosensitizers to form a p-n heterojunction (PFP/PDI) layer, affording higher hole/electron separation efficiency. The π-conjugated semiconductors possess excellent light-harvesting ability and biocompatibility, and the cationic side chains of organic semiconductors could intercalate into cell membranes, ensuring efficient electron transfer to bacteria. Moorella thermoacetica can thus harvest photoexcited electrons from the PFP/PDI heterojunction, driving the Wood-Ljungdahl pathway to synthesize acetic acid from CO under illumination. The efficiency of this organic biohybrid is about 1.6 %, which is comparable to those of reported inorganic biohybrid systems.
一种有机半导体-细菌生物杂交光合系统被用于高效地实现将CO还原，从而利用非光合细菌嗜热栖热放线菌生产乙酸。苝二酰亚胺衍生物（PDI）和聚（芴-共-亚苯基）（PFP）作为光敏剂被包覆在细菌表面，以形成一个p-n异质结（PFP/PDI）层，从而提供更高的空穴/电子分离效率。π共轭半导体具有优异的光捕获能力和生物相容性，并且有机半导体的阳离子侧链可以插入细胞膜，确保向细菌的有效电子转移。因此，嗜热栖热放线菌可以从PFP/PDI异质结收集光激发电子，在光照下驱动伍德-Ljungdahl途径从CO合成乙酸。这种有机生物杂交体的效率约为1.6%，与已报道的无机生物杂交系统相当。
