Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
Department of Otorhinolaryngology, Jena University Hospital, Am Klinikum 1, 07747, Jena, Germany.
Eur Arch Otorhinolaryngol. 2020 May;277(5):1409-1415. doi: 10.1007/s00405-020-05846-7. Epub 2020 Feb 18.
This paper describes a first attempt to quantify LEMG data based on turn number calculation. The results obtained for both healthy and ailing thyroarytenoid (TA) muscles of patients with unilateral vocal fold immobility (UVFI) were compared with the respective qualitative evaluation concerning volitional activity to determine whether the two types of analyses deliver similar results.
LEMG data obtained from 44 adults with UVFI were considered for the study. Semiquantitative evaluation of TA volitional activity and turn number were assessed for the ailing and the healthy TA and the difference in percentage was calculated. Paired data were compared with the Wilcoxon signed-rank test. The volitional activity assessment and the turn number evaluation were compared with the Kruskal-Wallis test, and their relationship was tested with the Kendall rank correlation.
Datasets of 27 patients were considered compatible with turns/s calculation. The results showed that complete paralysis correlated with no turns; single fiber volitional activity with 62-208 turns/s, strongly decreased volitional activity with 198-501 turns/s; and dense volitional activity with 441-1234 turns/s. On the ailing VF only, the Kruskal-Wallis test showed a statistically significant difference (p = 0.0001), and the Kendall rank correlation a positive relationship (r = 0.853,p ≤ 0.0001) between the volitional activity rating and the turn number assessment.
Our preliminary results showed that turn number evaluation is an effective tool to confirm LEMG qualitative analysis, and that, in combination with laryngostroboscopy and voice assessment, can help improving the accuracy of the diagnosis and prognosis and the effectiveness of the chosen therapy.
本文首次尝试基于转动次数计算对肌电图数据进行量化。将单侧声带不动患者（UVFI）健康和患病的甲状腺动肌（TA）的结果与关于随意活动的相应定性评估进行比较，以确定两种分析是否提供类似的结果。
对 44 名患有 UVFI 的成年人进行了肌电图数据研究。评估患病和健康 TA 的 TA 随意活动和转动次数的半定量评估，并计算差异百分比。对配对数据进行 Wilcoxon 符号秩检验比较。使用 Kruskal-Wallis 检验比较随意活动评估和转动次数评估，并使用 Kendall 秩相关检验测试它们之间的关系。
考虑到有 27 名患者的数据集与转动/秒的计算兼容。结果表明，完全瘫痪与无转动相关；单纤维随意活动与 62-208 转/秒相关，强烈减少的随意活动与 198-501 转/秒相关；密集的随意活动与 441-1234 转/秒相关。仅在患病的声带上，Kruskal-Wallis 检验显示出统计学上的显著差异（p=0.0001），Kendall 秩相关显示出随意活动评分和转动次数评估之间存在正相关（r=0.853，p≤0.0001）。
我们的初步结果表明，转动次数评估是确认肌电图定性分析的有效工具，并且与频闪喉镜和语音评估相结合，可以帮助提高诊断和预后的准确性，以及所选治疗的有效性。
