Finsterer J, Mamoli B, Fuglsang-Frederiksen A
Ludwig Boltzmann Institute for Research in Epilepsy and Neuromuscular Disorders, Vienna, Austria.
Electroencephalogr Clin Neurophysiol. 1997 Oct;105(5):379-84. doi: 10.1016/s0924-980x(97)00039-8.
Peak-ratio interference pattern analysis (peak-ratio method) is said to have a high sensitivity and to be independent of sex and age. This study was carried out to prove or disprove these findings. The peak-ratio method and qualitative motor unit action potential (MUAP) analysis were applied to the right brachial biceps and anterior tibial muscles of 44 healthy subjects, aged 23-87 years, 25 neuropathy patients, aged 21-83 years, and 29 myopathy patients, aged 19-70 years. Peak-ratio parameters were independent of sex and age. They tended to be lower in the anterior tibial muscle than in the brachial biceps muscle. Neuropathy patients typically showed decreased peak-ratio, short time intervals and increased amplitude/turn. Myopathy patients typically showed increased peak-ratio, turns/s and short time intervals. The sensitivity of the peak-ratio method was 72% for neuropathy patients and 59% for myopathy patients. The sensitivity of the peak-ratio method was similar to that of the MUAP analysis in neuropathy patients and higher than that of the MUAP analysis in myopathy patients. The specificity of the peak-ratio method was 80%. The peak-ratio method proved to be a valuable, supplementary electromyographic tool for the detection of neuromuscular disorders.
峰比值干扰模式分析（峰比值法）据称具有高灵敏度，且与性别和年龄无关。本研究旨在验证或反驳这些发现。对44名年龄在23 - 87岁的健康受试者、25名年龄在21 - 83岁的神经病变患者以及29名年龄在19 - 70岁的肌病患者的右侧肱二头肌和胫前肌应用了峰比值法和定性运动单位动作电位（MUAP）分析。峰比值参数与性别和年龄无关。它们在胫前肌中的值往往低于肱二头肌中的值。神经病变患者通常表现为峰比值降低、时间间隔缩短以及波幅/转折增加。肌病患者通常表现为峰比值增加、每秒转折数增加以及时间间隔缩短。峰比值法对神经病变患者的灵敏度为72%，对肌病患者为59%。峰比值法在神经病变患者中的灵敏度与MUAP分析相似，在肌病患者中则高于MUAP分析。峰比值法的特异性为80%。峰比值法被证明是检测神经肌肉疾病的一种有价值的辅助肌电图工具。
