中国携带该基因的具有多重耐药特性的产硫化氢（HS）新变体的基因组特征†
Genomic Characterization of New Variant of Hydrogen Sulfide (HS)-Producing with Multidrug Resistance Properties Carrying the Gene in China †.
作者信息
Biswas Silpak, Elbediwi Mohammed, Gu Guimin, Yue Min
机构信息
Institute of Preventive Veterinary Sciences & Department of Veterinary Medicine, Zhejiang University College of Animal Sciences, Hangzhou 310007, China.
Animal Health Research Institute, Agriculture Research Centre, Cairo 11435, Egypt.
出版信息
Antibiotics (Basel). 2020 Feb 13;9(2):80. doi: 10.3390/antibiotics9020080.
Abstract
Colistin is considered to be a 'last-resort' antimicrobial for the treatment of multidrug-resistant Gram-negative bacterial infections. Identification of , carrying the transferable colistin resistance gene , has recently provoked a global health concern. This report presents the first detection of a hydrogen sulfide (HS)-producing variant isolated from a human in China, with multidrug resistance (MDR) properties, including colistin resistance by the gene, which could have great implications for the treatment of human infections.
摘要
黏菌素被认为是治疗多重耐药革兰氏阴性菌感染的“最后一道防线”抗菌药物。携带可转移黏菌素耐药基因的[具体细菌名称未给出]的鉴定最近引发了全球健康关注。本报告首次在中国检测到一株从人类分离出的产硫化氢（H₂S）的[具体细菌名称未给出]变体，它具有多重耐药（MDR）特性，包括通过[具体基因名称未给出]基因产生黏菌素耐药性，这可能对人类感染的治疗产生重大影响。
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