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精神病理学的个性化模型。

Personalized Models of Psychopathology.

机构信息

Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA; email:

出版信息

Annu Rev Clin Psychol. 2020 May 7;16:49-74. doi: 10.1146/annurev-clinpsy-102419-125032. Epub 2020 Feb 18.

Abstract

The personalized approach to psychopathology conceptualizes mental disorder as a complex system of contextualized dynamic processes that is nontrivially specific to each individual, and it seeks to develop formal idiographic statistical models to represent these individual processes. Although the personalized approach draws on long-standing influences in clinical psychology, there has been an explosion of research in recent years following the development of intensive longitudinal data capture and statistical techniques that facilitate modeling of the dynamic processes of each individual's pathology. Advances are also making idiographic analyses scalable and generalizable. We review emerging research using the personalized approach in descriptive psychopathology, precision assessment, and treatment selection and tailoring, and we identify future challenges and areas in need of additional research. The personalized approach to psychopathology holds promise to resolve thorny diagnostic issues, generate novel insights, and improve the timing and efficacy of interventions.

摘要

个性化的精神病理学方法将精神障碍视为一种复杂的语境化动态过程系统,这种系统对于每个个体来说都具有重要意义。它旨在开发正式的个体化统计模型来表示这些个体的过程。尽管个性化方法受到临床心理学中由来已久的影响,但近年来,随着密集纵向数据捕获和统计技术的发展,促进了个体病理学动态过程的建模,该方法的研究也呈爆炸式增长。此外,进展也使得个体化分析具有可扩展性和通用性。我们综述了在描述性精神病理学、精确评估以及治疗选择和调整中使用个性化方法的新兴研究,并确定了未来需要进一步研究的挑战和领域。个性化的精神病理学方法有望解决棘手的诊断问题,产生新的见解,并提高干预的时间和效果。

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