Allergy Clinic, Casa di Cura Villa Montallegro, Genoa, Italy.
Pediatric Allergy Center, Istituto G. Gaslini, Genoa, Italy.
Acta Biomed. 2020 Feb 17;91(1-S):43-47. doi: 10.23750/abm.v91i1-S.9254.
Allergic rhinitis (AR) is the most common immune-mediated disorder in childhood as it may affect up to 40% of children. Turbinate hypertrophy (TH) is an important sign as reliably predicts AR both in children and adults. Consistently, nasal obstruction is a very common symptom in AR patients and is closely linked with turbinate hypertrophy. This study investigated 544 (304 males) children with AR to define factors associated with TH. TH was diagnosed in 438 (80.81%) AR children. The multivariate analysis demonstrated a significant association between age, male gender, and recurrent acute otitis media (RAOM), and TH (p-values: 0.0219, <0.0001, and 0.0003, respectively; OR 0.87, 3.97, and 0.22 respectively). In conclusion, this real-life study showed that TH was very frequent in children with AR and age, male gender, and RAOM were significantly associated with TH.
变应性鼻炎（AR）是儿童中最常见的免疫介导性疾病，它可能影响多达 40%的儿童。鼻甲肥大（TH）是一个重要的体征，因为它可靠地预测了儿童和成人的 AR。一致的是，鼻塞是 AR 患者的常见症状，与鼻甲肥大密切相关。本研究调查了 544 名（304 名男性）患有 AR 的儿童，以确定与 TH 相关的因素。TH 被诊断为 438 名（80.81%）AR 儿童。多变量分析表明，年龄、男性性别和复发性急性中耳炎（RAOM）与 TH 之间存在显著关联（p 值分别为 0.0219、<0.0001 和 0.0003；OR 分别为 0.87、3.97 和 0.22）。总之，这项真实世界的研究表明，TH 在患有 AR 的儿童中非常常见，年龄、男性性别和 RAOM 与 TH 显著相关。
