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在脊髓刺激术中使用右美托咪定进行清醒镇静可改善手术桨状导联放置的结果:25 例连续患者的病例系列。

Conscious Sedation Using Dexmedetomidine During Surgical Paddle Lead Placement Improves Outcome in Spinal Cord Stimulation: A Case Series of 25 Consecutive Patients.

机构信息

Department of Neurosurgery, AZ Delta Roeselare-Torhout-Menen, Roeselare, Belgium.

Department of Anesthesiology and Pain Clinic, AZ Delta Roeselare-Torhout-Menen, Roeselare, Belgium.

出版信息

Neuromodulation. 2021 Dec;24(8):1347-1350. doi: 10.1111/ner.13124. Epub 2020 Feb 19.

DOI:10.1111/ner.13124
PMID:32074387
Abstract

OBJECTIVES

Different anesthesia techniques are used for surgical implantation of paddle lead electrodes for neurostimulation through a laminectomy. We wanted to evaluate the use of dexmedetomidine as sedative for this procedure in a series of patients. Second, we wanted to verify whether the stimulation pattern and position of the electrode had to be changed during the procedure guided by the patient's feedback.

MATERIAL AND METHODS

Twenty-five consecutive patients received surgical implantation of a spinal cord stimulation electrode under conscious sedation using dexmedetomidine and local anesthesia. We evaluated the effects of the administered drug, the patient comfort, and the adequacy of the stimulation pattern.

RESULTS

Twenty-four patients completed the procedure with only dexmedetomidine and local anesthetic. Infusion was started on average 55 minutes (sd 29) prior to incision. The mean dose of lidocaine was 430 mg (sd 95). There were no significant hemodynamic changes. Median time to reach Modified Aldrete's score postoperative was 67 minutes (sd 38). In 46% of the patients, the position of the electrode was changed guided by the feedback of the patient. More than half of the patients remember most details of the procedure. Only four patients mentioned substantial discomfort and only three would definitely not want to undergo this procedure again.

CONCLUSIONS

Implantation of spinal cord stimulation electrodes through a surgical laminectomy using dexmedetomidine is a safe and feasible procedure with adequate comfort for patient and surgeon. This way of working increases the optimal position of the electrode resulting in the most convenient stimulation pattern and avoiding revisions.

摘要

目的

神经刺激的经皮穿刺术采用不同的麻醉技术来植入桨形导联电极。我们想评估在一系列患者中使用右美托咪定作为镇静剂进行此手术的效果。其次,我们想验证在患者的反馈指导下,是否必须改变电极的刺激模式和位置。

材料和方法

25 例连续患者在局部麻醉下接受右美托咪定清醒镇静下的脊髓刺激电极植入术。我们评估了所使用药物的效果、患者的舒适度和刺激模式的充分性。

结果

24 例患者仅使用右美托咪定和局部麻醉完成了手术。在切开前平均 55 分钟(标准差 29)开始输注。利多卡因的平均剂量为 430mg(标准差 95)。无明显的血流动力学变化。达到改良 Aldrete 评分的中位数时间为术后 67 分钟(标准差 38)。在 46%的患者中,电极的位置根据患者的反馈进行了改变。超过一半的患者记得手术的大部分细节。只有 4 名患者提到了明显的不适,只有 3 名患者肯定不想再次接受此手术。

结论

在使用右美托咪定进行经皮穿刺脊髓刺激电极植入术是一种安全可行的方法,可使患者和外科医生都感到舒适。这种工作方式增加了电极的最佳位置,从而产生了最方便的刺激模式,并避免了修订。

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