Kaya Uğur, Çolak Abdurrahim, Becit Necip, Ceviz Münacettin, Koçak Hikmet
Department of Cardiovascular Surgery, Medicine Faculty of Atatürk University, Erzurum, Turkey.
Turk Gogus Kalp Damar Cerrahisi Derg. 2018 Apr 30;26(2):167-176. doi: 10.5606/tgkdc.dergisi.2018.15004. eCollection 2018 Apr.
This study aims to evaluate the effects of graft dysfunction detected by intraoperative transit-time flow measurement on the outcomes of on-pump coronary artery bypass graft surgery.
A total of 1,240 patients (856 males, 384 females; mean age 57.4±12.1 years; range, 47 to 74 years), who underwent isolated on-pump coronary artery bypass graft surgery via median sternotomy performed by the same surgical team, were reviewed retrospectively. With the introduction of transit-time flow measurement into practice at our clinic in 2006, all patients regularly underwent transit-time flow measurement during surgery in order to evaluate the graft patency. Interpretation of the data obtained using the transit-time flow measurement in patients who underwent surgery has directed our decision as to whether to perform graft revision. Patients were evaluated for early- and late-period mortality/ morbidity, perioperative and postoperative myocardial infarction, and intraaortic balloon requirement.
A total of 3,596 grafts in the perioperative period was evaluated using transit-time flow measurement. Anastomosis/graft revision, new anastomosis/patch plasty to distal native artery or free left internal mammary artery graft was performed in 146 grafts of 143 patients in whom transittime flow measurement showed insufficient patency. Four of six patients who developed peri/postoperative myocardial infarction were found to have perioperative hypotension, ST elevation, and wall motion abnormality on transesophageal echocardiography before closure of the sternum. The flow was corrected by extending the short length of the grafts with insufficient flow after transit-time flow measurement and it was recorded that transit-time flow measurements were at normal values at these four grafts. Two patients developed acute myocardial infarction in the postoperative period and stent was applied in one vessel of each patient; however, one of these patients died. Sixteen patients were inserted intraaortic balloon pump, four of which being in the preoperative period. Revision surgery was performed due to bleeding in 56 patients and sternal infection in 12 patients. Of all patients, 28 (2.3%) died in the early postoperative period.
We believe that transit-time flow measurement may be an important tool in evaluating graft function and contribute to eliminate the causes of graft failure during surgery.
本研究旨在评估术中通过渡越时间血流测量检测到的移植物功能障碍对体外循环冠状动脉搭桥手术结果的影响。
回顾性分析了由同一手术团队经正中胸骨切开术进行单纯体外循环冠状动脉搭桥手术的1240例患者(男性856例,女性384例;平均年龄57.4±12.1岁;范围47至74岁)。自2006年我院将渡越时间血流测量应用于临床实践以来,所有患者在手术期间均定期进行渡越时间血流测量以评估移植物通畅情况。对接受手术患者使用渡越时间血流测量获得的数据进行解读,指导了我们关于是否进行移植物修复的决策。对患者进行早期和晚期死亡率/发病率、围手术期和术后心肌梗死以及主动脉内球囊使用情况的评估。
围手术期共使用渡越时间血流测量评估了3596根移植物。在143例患者的146根移植物中,当渡越时间血流测量显示通畅不足时,进行了吻合口/移植物修复、新的吻合口/向远端自体动脉或游离左乳内动脉移植物的补片成形术。在6例发生围手术期/术后心肌梗死的患者中,有4例在胸骨关闭前经食管超声心动图检查发现围手术期低血压、ST段抬高和室壁运动异常。在渡越时间血流测量后,通过延长血流不足的移植物的短长度纠正了血流,并记录到这4根移植物的渡越时间血流测量值为正常。2例患者在术后发生急性心肌梗死,每位患者的一根血管置入了支架;然而,其中1例患者死亡。16例患者置入了主动脉内球囊泵,其中4例在术前。56例患者因出血进行了修复手术,12例患者因胸骨感染进行了手术。所有患者中,28例(2.3%)在术后早期死亡。
我们认为,渡越时间血流测量可能是评估移植物功能的重要工具,并有助于消除手术期间移植物失败的原因。