Packham D K, North R A, Fairley K F, Whitworth J A, Kincaid-Smith P
Department of Nephrology, Royal Melbourne Hospital, Parkville, Victoria, Australia.
Clin Nephrol. 1988 Jul;30(1):15-21.
One hundred and sixteen pregnancies in 70 women with a biopsy-proven diagnosis of IgA glomerulonephritis have been analysed. Thirty percent (35) of the fetuses died, 22% (26) were premature and 44% (52) were full term. Maternal renal function declined during pregnancy in 26% (30) and in 2% (2) this was irreversible post-partum. Hypertension developed in 52% (61) of the pregnancies and in 13% (15) this was irreversible. Increased proteinuria was recorded in 62% (74) of the pregnancies. Fetal loss in pregnancies taking place after biopsy diagnosis was lower (16%) than those in which biopsy was performed either during or following the pregnancy (36%).
对70例经活检确诊为IgA肾小球肾炎的女性的116次妊娠进行了分析。30%（35例）胎儿死亡，22%（26例）早产，44%（52例）足月产。26%（30例）孕妇的肾功能在孕期下降，其中2%（2例）产后不可逆转。52%（61例）的妊娠出现高血压，其中13%（15例）不可逆转。62%（74例）的妊娠蛋白尿增加。活检诊断后妊娠的胎儿丢失率（16%）低于妊娠期间或妊娠后进行活检的胎儿丢失率（36%）。
