Blott M, Greenough A
Department of Child Health, King's College Hospital, London, U.K.
Early Hum Dev. 1988 May;17(1):37-40. doi: 10.1016/s0378-3782(88)80055-0.
Two patients with severe oligohydramnios in the second trimester, one due to spontaneous membrane rupture at 18 weeks and the other, uteroplacental insufficiency from 22 weeks were prospectively followed. In both cases despite severe oligohydramnios fetal breathing movements persisted and although one infant delivered at 28 weeks developed respiratory distress syndrome and the second meconium aspiration syndrome neither had evidence of pulmonary hypoplasia. We conclude the presence of fetal breathing movements, despite oligohydramnios, may preserve lung growth, and may act as a predictor of favourable neonatal outcome.
两名孕中期严重羊水过少的患者，一名在孕18周时胎膜自发破裂，另一名在孕22周时出现子宫胎盘功能不全，对她们进行了前瞻性随访。在这两个病例中，尽管羊水过少，但胎儿呼吸运动持续存在，虽然一名在28周出生的婴儿发生了呼吸窘迫综合征，另一名发生了胎粪吸入综合征，但两者均无肺发育不全的证据。我们得出结论，尽管羊水过少，但胎儿呼吸运动的存在可能会维持肺的生长，并可作为新生儿良好结局的预测指标。
