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[叙利亚仓鼠血液中性粒细胞和腹膜渗出细胞对腹腔注射细胞和微生物物质的化学发光反应]

[The chemiluminescence reactions of the blood neutrophils and of peritoneal exudate cells in Syrian hamsters to the intraperitoneal administration of cellular and microbial materials].

作者信息

Prilutskaia M O, Kashkina L M

出版信息

Biull Eksp Biol Med. 1992 Nov;114(11):515-8.

PMID:1290827
Abstract

The luminol-dependent chemiluminescence (CL) activity of peritoneal exudate cells and blood neutrophils of Syrian hamsters inoculated intraperitoneally with heat-inactivated microbial particles of Candida albicans, (C. albicans), heated irradiated normal cells and native or heated irradiated malignant tumor cells was studied. The inoculation with particles of C. albicans and heated normal cells induced significant activation of CL of peritoneal exudate cells, but did not influence the CL reaction of blood neutrophils. The inoculation of animals with nonheated irradiated tumor cells led to increase of CL response of both peritoneal exudate cells and blood neutrophils. The inoculation with heated irradiated tumor cells did not activate CL of peritoneal exudate cells and led to slight, but long-lasting decrease of CL response of blood neutrophils.

摘要

研究了腹腔注射热灭活白色念珠菌(C. albicans)微生物颗粒、热辐照正常细胞以及天然或热辐照恶性肿瘤细胞的叙利亚仓鼠腹腔渗出细胞和血液中性粒细胞的鲁米诺依赖性化学发光(CL)活性。接种白色念珠菌颗粒和热辐照正常细胞可显著激活腹腔渗出细胞的CL,但不影响血液中性粒细胞的CL反应。给动物接种未加热辐照的肿瘤细胞会导致腹腔渗出细胞和血液中性粒细胞的CL反应增强。接种热辐照肿瘤细胞不会激活腹腔渗出细胞的CL,并导致血液中性粒细胞的CL反应轻微但持续降低。

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