Department of Transplantation and Vascular Surgery, Korea University College of Medicine, Seoul, Korea.
Department of Biostatistics, Korea University College of Medicine, Seoul, Korea.
BMC Cardiovasc Disord. 2020 Feb 22;20(1):87. doi: 10.1186/s12872-020-01389-1.
The purpose of this study was to confirm that inequalities in community-level social economic status (SES) do actually impact the incidence of ischemic heart disease (IHD) using the Korean population-based cohort study of the National Health Insurance Service-National Sample Cohort (NHIS-NSC) database.
This study used the NHIS-NSC database, a population-based cohort database established by the NHIS in South Korea. Community-level SES was classified into three categories, i.e. low, moderate, and high, according to the rank. The outcome measure of interest was IHD, which was defined according to the International Classification of Disease, 10th Revision (ICD-10) codes.
In the low community-level SES group, the incidence of IHD was 3.56 per 1000 person years (cumulative incidence rate, 1.78%), and in the high community level SES group, it was 3.13 per 1000 person years (cumulative incidence rate, 1.57%). Multivariate analysis showed that the incidence of IHD was higher in the low community-level SES group (p = 0.029). The log-rank test showed that the cumulative incidence of IHD was higher in the low community level SES group than the high community-level SES group (adjusted hazard ratio, 1.16; 95% CI, 1.01-1.32).
People living in areas with low community-level SES show an increased incidence of IHD. Therefore, intervention in active, health-risk behavior corrections at the local level will be required to reduce the incidence of IHD.
本研究旨在利用韩国国民健康保险服务-国家样本队列(NHIS-NSC)数据库中的基于人群的队列研究,证实社区社会经济地位(SES)不平等实际上会对缺血性心脏病(IHD)的发病率产生影响。
本研究使用了 NHIS-NSC 数据库,这是韩国国民健康保险服务建立的基于人群的队列数据库。根据等级将社区 SES 分为低、中、高三类。感兴趣的结局指标是 IHD,其根据国际疾病分类,第 10 版(ICD-10)代码定义。
在低社区 SES 组中,IHD 的发病率为 3.56/1000 人年(累积发病率为 1.78%),而在高社区 SES 组中,发病率为 3.13/1000 人年(累积发病率为 1.57%)。多变量分析表明,低社区 SES 组的 IHD 发病率更高(p=0.029)。对数秩检验表明,低社区 SES 组的 IHD 累积发病率高于高社区 SES 组(调整后的危险比为 1.16;95%置信区间,1.01-1.32)。
生活在社区 SES 较低地区的人患 IHD 的发病率增加。因此,需要在地方一级进行积极的健康风险行为纠正干预,以降低 IHD 的发病率。