Li Wendy, Frech Tracy M
Indiana University School of Medicine, Indianapolis, Indiana - USA.
Systemic Sclerosis Clinic, University of Utah, Department of Internal Medicine, Division of Rheumatology, Salt Lake City, Utah - USA.
J Scleroderma Relat Disord. 2017 May;2(2):69-71. doi: 10.5301/jsrd.5000238. Epub 2017 May 19.
Digital ulcers are one of the key predictors of disease progression and quality of life in patients with systemic sclerosis. Choosing the right treatment for the individual patient begins at developing a consensus among clinicians of what constitutes a digital ulcer. The aim of this editorial is to describe the high unmet need for a standardized method of defining digital ulcers, which is a major challenge not only for treatment, but also for development of new therapies. We discuss the potential role of ultrasound in the development of a validated definition of digital ulcers in systemic sclerosis.
指端溃疡是系统性硬化症患者疾病进展和生活质量的关键预测指标之一。为个体患者选择合适的治疗方法，首先要在临床医生之间就什么构成指端溃疡达成共识。本社论的目的是描述对定义指端溃疡的标准化方法的高度未满足需求，这不仅是治疗面临的重大挑战，也是新疗法研发面临的重大挑战。我们讨论了超声在制定系统性硬化症指端溃疡有效定义方面的潜在作用。
