Fallowfield M E, Dodson A R, Cook M G
Department of Histopathology, St George's Hospital, London, UK.
Histopathology. 1988 Jul;13(1):95-9. doi: 10.1111/j.1365-2559.1988.tb02007.x.
Using silver (Ag) staining to demonstrate nucleolar organizer region-associated proteins (AgNORs), pigmented naevi exhibiting features of melanocytic dysplasia have been examined and compared with benign intradermal and compound naevi and with malignant melanomas. A highly significant difference was found between the numbers of AgNORs demonstrated in benign naevus cells and atypical melanocytes and in malignant melanocytes, suggesting that this technique may have a role in differentiating between difficult melanocytic lesions.
运用银（Ag）染色法来显示核仁组成区相关蛋白（AgNORs），对呈现黑素细胞发育异常特征的色素痣进行了检查，并与良性皮内痣、复合痣以及恶性黑色素瘤进行了比较。结果发现，良性痣细胞、非典型黑素细胞和恶性黑素细胞中所显示的AgNORs数量存在高度显著差异，这表明该技术可能在鉴别疑难黑素细胞性病变方面具有一定作用。
