Department of Neurology, Soonchunhyang University Seoul Hospital, Soonchunhyang University School of Medicine, Seoul, Korea.
Department of Biostatistics, Soonchunhyang University Hospital, Soonchunhyang University School of Medicine, Seoul, Korea.
Geriatr Gerontol Int. 2020 May;20(5):443-447. doi: 10.1111/ggi.13894. Epub 2020 Feb 24.
The clinical features and implications of dizziness in patients with Parkinson's disease (PD) remain little known. This study aimed to investigate the clinical characteristics of dizziness, and the association of dizziness with motor and non-motor symptoms in early stages of PD.
Demographics and clinical characteristics of patients with early PD (disease duration ≤5 years) were retrospectively assessed. The characteristics of dizziness were surveyed in each parkinsonian patient according to existence, frequency, duration and nature. Not only motor symptoms, but also non-motor scales for global cognition, anxiety, depression and fatigue were evaluated to identify risk factors of dizziness.
Of a total of 80 patients with early PD, 37 (46.3%) had dizziness. The characteristics of dizziness included short duration (seconds to minutes) and frequent occurrence (several times in a day or a week). The most common type of dizziness was orthostatic (40.5%), followed by non-specific and disequilibrium type. Among many scales for motor and non-motor symptoms, dizzy patients with early PD showed lower scores of Montreal Cognitive representing global cognition than non-dizzy people. A lower Montreal Cognitive Assessment score was the only factor significantly related to dizziness in patients with early PD.
We found that dizziness frequently occurs in early parkinsonian patients. It is highly linked to low Montreal Cognitive Assessment scores in patients with early PD, inferring that dizziness might be a potential non-motor symptom associated with cognitive decline in PD. Geriatr Gerontol Int 2020; 20: 443-447.
帕金森病（PD）患者头晕的临床特征和意义仍知之甚少。本研究旨在探讨早期 PD 患者头晕的临床特征，以及头晕与运动和非运动症状的关系。
回顾性评估早期 PD 患者（病程≤5 年）的人口统计学和临床特征。根据存在、频率、持续时间和性质，对每位帕金森病患者的头晕特征进行调查。不仅评估运动症状，还评估整体认知、焦虑、抑郁和疲劳的非运动量表，以确定头晕的危险因素。
在总共 80 名早期 PD 患者中，有 37 名（46.3%）有头晕。头晕的特征包括持续时间短（数秒至数分钟）和频繁发生（每天或每周几次）。最常见的头晕类型是体位性（40.5%），其次是非特异性和不平衡性。在许多运动和非运动症状量表中，早期 PD 伴头晕的患者的蒙特利尔认知评分代表整体认知的得分低于不伴头晕的患者。蒙特利尔认知评估评分较低是与早期 PD 患者头晕相关的唯一显著因素。
我们发现头晕在早期帕金森病患者中经常发生。它与早期 PD 患者的蒙特利尔认知评估评分较低高度相关，表明头晕可能是 PD 认知下降相关的潜在非运动症状。老年医学与老年病学杂志 2020；20：443-447。
