Programa de Pós-Graduação em Ciências Farmacêuticas, Universidade Federal do Pará, Belém 66075-900, Brazil.
Laboratório de Bioprospecção e Biologia Experimental, Universidade Federal do Oeste do Pará, Santarém 68035-110, Brazil.
Biomolecules. 2020 Feb 19;10(2):328. doi: 10.3390/biom10020328.
The essential oil of has been attributed anti-depressive, antinociceptive, antileishmanial, larvicidal, antioxidant, antibacterial, and antifungal activities. It is known that the cultivation of this plant can be affected by seasonality, promoting alteration in the oil composition and its biological activities. This study aims to perform the annual evaluation of the curzerene-type oil of and determine its antioxidant activity. The oil yield from the dry season (1.4 ± 0.6%) did not differ statistically from that of the rainy season (1.8 ± 0.8%). Curzerene, an oxygenated sesquiterpene, was the principal constituent, and its percentage showed no significant difference between the two periods: dry (42.7% ± 6.1) and rainy (40.8 ± 5.9%). Principal component and hierarchical cluster analyses presented a high level of similarity between the monthly samples of the oils. Also, in the annual study, the yield and composition of the oils did not present a significant correlation with the climatic variables. The antioxidant activity of the oils showed inhibition of DPPH radicals with an average value of 55.0 ± 6.6%. The high curzerene content in the monthly oils of suggests their potential for use as a future phytotherapeutic alternative.
已经发现，这种植物的种植会受到季节性的影响，从而导致油的成分及其生物活性发生变化。本研究旨在对 curzerene 型 的年度评估，并确定其抗氧化活性。旱季（1.4±0.6%）的产油量与雨季（1.8±0.8%）相比没有统计学差异。氧代倍半萜 curzerene 是主要成分，其百分率在两个时期之间没有显著差异：旱季（42.7%±6.1）和雨季（40.8±5.9）。主成分和层次聚类分析表明，油的每月样本之间具有高度相似性。此外，在年度研究中，油的产量和成分与气候变量之间没有显著相关性。油的抗氧化活性显示出对 DPPH 自由基的抑制作用，平均抑制率为 55.0±6.6%。每月油中高含量的 curzerene 表明它们具有作为未来植物治疗替代物的潜力。
