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截至2018年:对……属生物分子序列的一项调查。 (原文中“genus ”后缺少具体内容)

Till 2018: a survey of biomolecular sequences in genus .

作者信息

Boopathi Vinothini, Subramaniyam Sathiyamoorthy, Mathiyalagan Ramya, Yang Deok-Chun

机构信息

Graduate School of Biotechnology, College of Life Sciences, Kyung Hee University, Yongin, Republic of Korea.

Research and Development Center, Insilicogen Inc., Yongin, Republic of Korea.

出版信息

J Ginseng Res. 2020 Jan;44(1):33-43. doi: 10.1016/j.jgr.2019.06.004. Epub 2019 Jun 20.

Abstract

Ginseng is popularly known to be the king of ancient medicines and is used widely in most of the traditional medicinal compositions due to its various pharmaceutical properties. Numerous studies are being focused on this plant's curative effects to discover their potential health benefits in most human diseases, including cancer- the most life-threatening disease worldwide. Modern pharmacological research has focused mainly on ginsenosides, the major bioactive compounds of ginseng, because of their multiple therapeutic applications. Various issues on ginseng plant development, physiological processes, and agricultural issues have also been studied widely through state-of-the-art, high-throughput sequencing technologies. Since the beginning of the 21st century, the number of publications on ginseng has rapidly increased, with a recent count of more than 6,000 articles and reviews focusing notably on ginseng. Owing to the implementation of various technologies and continuous efforts, the ginseng plant genomes have been decoded effectively in recent years. Therefore, this review focuses mainly on the cellular biomolecular sequences in ginseng plants from the perspective of the central molecular dogma, with an emphasis on genomes, transcriptomes, and proteomes, together with a few other related studies.

摘要

人参被誉为古代药物之王,由于其多种药用特性,在大多数传统药物配方中被广泛使用。众多研究聚焦于这种植物的治疗效果,以发现其在包括癌症(全球最具生命威胁的疾病)在内的大多数人类疾病中的潜在健康益处。现代药理学研究主要集中在人参的主要生物活性成分人参皂苷上,因为它们具有多种治疗应用。通过先进的高通量测序技术,人参植物发育、生理过程及农业相关的各种问题也得到了广泛研究。自21世纪初以来,关于人参的出版物数量迅速增加,最近统计有超过6000篇文章和综述特别关注人参。由于各种技术的应用和持续努力,近年来人参植物基因组已被有效解码。因此,本综述主要从中枢分子生物学法则的角度,着重从基因组、转录组和蛋白质组方面,以及其他一些相关研究,聚焦人参植物中的细胞生物分子序列。

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