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人参衍生化合物在癌症中的功能作用。

Functional role of ginseng-derived compounds in cancer.

作者信息

Ahuja Akash, Kim Ji Hye, Kim Jong-Hoon, Yi Young-Su, Cho Jae Youl

机构信息

Department of Genetic Engineering, Sungkyunkwan University, Suwon, Republic of Korea.

Department of Physiology, College of Veterinary Medicine, Chonbuk National University, Iksan, Republic of Korea.

出版信息

J Ginseng Res. 2018 Jul;42(3):248-254. doi: 10.1016/j.jgr.2017.04.009. Epub 2017 May 15.

DOI:10.1016/j.jgr.2017.04.009
PMID:29983605
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6026353/
Abstract

Ginseng is a natural product best known for its curative properties in diverse physiological processes such as cancer, neurodegenerative disorders, hypertension, and maintenance of hemostasis in the immune system. In previous decades, there have been some promising studies into the pharmacology and chemistry of ginseng components and the relationship between their structure and function. The emerging use of modified ginseng and development of new compounds from ginseng for clinical studies have been topics of study for many researchers. The present review deals with the anticancer, anti-inflammatory, antioxidant, and chemopreventive effects, and recent advances in microRNA technology related to red ginseng. The review also summarizes the current knowledge on the effect of ginsenosides in the treatment of cancer.

摘要

人参是一种天然产物,因其在多种生理过程中的治疗特性而闻名,这些生理过程包括癌症、神经退行性疾病、高血压以及免疫系统止血功能的维持。在过去几十年里,对人参成分的药理学、化学及其结构与功能之间的关系进行了一些有前景的研究。改良人参的新用途以及从人参中开发新化合物用于临床研究一直是许多研究人员的研究课题。本综述探讨了红参的抗癌、抗炎、抗氧化和化学预防作用,以及与红参相关的微小RNA技术的最新进展。该综述还总结了目前关于人参皂苷在癌症治疗中作用的知识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/381f/6026353/9f09d642213e/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/381f/6026353/18857d735071/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/381f/6026353/9f09d642213e/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/381f/6026353/18857d735071/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/381f/6026353/9f09d642213e/gr2.jpg

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