Wojnarowska F, Delacroix D, Gengoux P
Slade Hospital, Oxford, England.
J Cutan Pathol. 1988 Oct;15(5):272-5. doi: 10.1111/j.1600-0560.1988.tb00558.x.
The subclasses of the cutaneous IgA were studied in 8 patients with dermatitis herpetiformis and 4 with linear IgA disease. The cutaneous IgA in dermatitis herpetiformis consisted of both IgA1 and IgA2, although IgA1 predominated. This demonstrated that the IgA is polyclonal and may be both mucosal and blood derived. The IgA in linear IgA disease was exclusively IgA1, confirming previous work, and suggesting that mucosal IgA may not make a major contribution to the skin deposits.
对8例疱疹样皮炎患者和4例线状IgA疾病患者的皮肤IgA亚类进行了研究。疱疹样皮炎中的皮肤IgA由IgA1和IgA2组成，尽管IgA1占主导。这表明IgA是多克隆的，可能来源于黏膜和血液。线状IgA疾病中的IgA仅为IgA1，证实了之前的研究工作，并提示黏膜IgA可能对皮肤沉积物的形成贡献不大。
