University Hospital Centre Osijek, Osijek 31 000, Croatia.
Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek 31 000, Croatia.
Int J Environ Res Public Health. 2020 Feb 22;17(4):1417. doi: 10.3390/ijerph17041417.
The aim of this study was to examine the quality of life and to report on the utility and QALY measures in patients before and after coronary artery bypass grafting (CABG); to investigate whether the SF-12 is comparable with the SF-36 for measuring health-related quality of life of patients with CABG; and to determine the impact of individual predictors on poor quality of life assessment after rehabilitation. This prospective study was conducted between January 2017 and December 2018 at the University Hospital Center Osijek, at three time points: pre-operation, 1 month after surgery, and after rehabilitation. The study was conducted with the SF-36 and SF-12 health questionnaires on 47 participants. After rehabilitation, there was a significant improvement in all domains of quality of life. The highest score was given to the change in pain (BP); mean scores were 63.8 (95% CI 56.9 to 70.6) ( = 0.001). The lowest grade (the lowest quality) after rehabilitation was in the domain of limitations due to physical difficulties (RP); arithmetic mean was 48.5 (95% CI 41 to 55.9) ( < 0.001). Quality-adjusted life-year was 0.41 (95% CI 0.38-0.44) after the CABG. The results of this study show that patients with coronary heart disease have poor quality of life before surgery. One month after the surgery, the quality of life improved, but was still inadequate. One year after surgery, satisfactory results were obtained in almost all subscales. The SF-36, SF-12, and its components, can be used effectively in patients with CABG. Age, gender, lifestyle, and risk factors in our sample of participants are not predictors of poor quality of life assessment after rehabilitation.
本研究旨在探讨生活质量，并报告冠状动脉旁路移植术（CABG）前后患者的效用和 QALY 测量值；调查 SF-12 是否可与 SF-36 相媲美，用于衡量 CABG 患者的健康相关生活质量；并确定个体预测因子对康复后生活质量评估的不良影响。这项前瞻性研究于 2017 年 1 月至 2018 年 12 月在奥西耶克大学医院中心进行，共分为三个时间点：手术前、手术后 1 个月和康复后。研究使用 SF-36 和 SF-12 健康问卷对 47 名参与者进行了调查。康复后，所有生活质量领域均有显著改善。疼痛（BP）的变化得分最高，平均得分为 63.8（95%CI 56.9 至 70.6）（ = 0.001）。康复后质量最低（最低质量）的领域是身体困难导致的限制（RP）；算术平均值为 48.5（95%CI 41 至 55.9）（<0.001）。CABG 后质量调整生命年为 0.41（95%CI 0.38-0.44）。本研究结果表明，冠心病患者手术前生活质量较差。手术后一个月，生活质量有所改善，但仍不理想。手术后一年，几乎所有子量表都取得了满意的结果。SF-36、SF-12 及其组成部分可有效应用于 CABG 患者。年龄、性别、生活方式和风险因素在我们的研究参与者样本中不是康复后生活质量评估的预测因子。
