Bujang Mohamad Adam, Lai Wei Hong, Tiong Xun Ting, Ratnasingam Selvasingam, Kim Alex Ren Jye, Husin Masliyana, Jee Yvonne Yih Huan, Ahmad Nurul Fatma Diyana, Tan Clare Hui Hong, Yee Khoo Sing, Hon Yoon Khee, Yap Eileen Pin Pin, Johari Fazalena, Fong Alan Yean Yip
Clinical Research Centre, National Institutes of Health, Sarawak General Hospital, Ministry of Health Malaysia, Kuching, Sarawak, 93586, Malaysia.
Sarawak General Hospital, Ministry of Health Malaysia, Kuching, Sarawak, 93586, Malaysia.
BMC Public Health. 2025 Feb 4;25(1):443. doi: 10.1186/s12889-025-21475-3.
Chronic diseases are known to detrimentally impact an individual's quality of life (QOL) and well-being. Therefore, this study aims to evaluate the QOL and overall well-being among both healthy individuals and those with diverse primary diagnoses.
This is a cross-sectional study and data collection took place from May 2022 to May 2023. Information regarding healthy participants was gathered from healthcare workers without any comorbidities. Data for non-healthy participants were collected from individuals diagnosed with various conditions across four specialist clinics: nephrology, oncology, psychiatry, and cardiology. All participants completed the Significant Quality of Life Measures (SigQOLM), a comprehensive assessment tool consisting of 69 items that evaluate 18 domains of QOL and well-being.
The study included a total of 452 participants, with 284 (62.8%) classified as healthy. Among the non-healthy participants, 41 (9.1%) had end-stage renal diseases (ESRD), 48 (10.6%) were diagnosed with cancer, 40 (8.8%) had depressive disorder, and the remaining had heart disease (8.6%). Statistical analysis revealed significant differences (p < 0.001) between healthy and non-healthy participants in both overall SigQOLM scores and across all 18 domains of SigQOLM.
Generally, healthy participants also experienced excellent QOL and well-being. However, disparities in both QOL and overall well-being were evident among patients with various diagnoses. These findings provide valuable insights for medical practitioners and policy makers by enabling them to tailor interventions to enhance the QOL and well-being of their patients.
已知慢性病会对个人生活质量（QOL）和幸福感产生不利影响。因此，本研究旨在评估健康个体以及患有不同原发性疾病的个体的生活质量和总体幸福感。
这是一项横断面研究，数据收集于2022年5月至2023年5月进行。关于健康参与者的信息是从没有任何合并症的医护人员那里收集的。非健康参与者的数据是从四个专科诊所（肾病科、肿瘤科、精神科和心脏科）中被诊断患有各种疾病的个体那里收集的。所有参与者都完成了重要生活质量测量（SigQOLM），这是一个由69个项目组成的综合评估工具，用于评估生活质量和幸福感的18个领域。
该研究共纳入452名参与者，其中284名（62.8%）被归类为健康。在非健康参与者中，41名（9.1%）患有终末期肾病（ESRD），48名（10.6%）被诊断患有癌症，40名（8.8%）患有抑郁症，其余患有心脏病（8.6%）。统计分析显示，健康和非健康参与者在SigQOLM总体得分以及SigQOLM的所有18个领域中均存在显著差异（p < 0.001）。
一般来说，健康参与者的生活质量和幸福感也很高。然而，不同诊断的患者在生活质量和总体幸福感方面存在明显差异。这些发现为医生和政策制定者提供了有价值的见解，使他们能够制定针对性的干预措施，以提高患者的生活质量和幸福感。
