Wilson Kate, Ellsworth Lindsay, Pesch Megan H
Division of Neonatal Perinatal Medicine, Department of Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USA.
Division of Developmental and Behavioral Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USA.
Case Rep Pediatr. 2020 Feb 12;2020:2534629. doi: 10.1155/2020/2534629. eCollection 2020.
Congenital cytomegalovirus infection (cCMV) is very common, yet the presentation can be varied, making the diagnosis challenging. However, early diagnosis for treatment with medication in symptomatic cases within the first month of life is critical. Hyperbilirubinemia and splenomegaly are less common manifestations at birth and may be overlooked in the setting of other symptoms, especially in a critically ill neonate. We present a case of a term infant with trisomy 21 who presented with isolated hyperbilirubinemia and splenomegaly and was later diagnosed with congenital CMV.
先天性巨细胞病毒感染（cCMV）非常常见，但其表现可能多种多样，这使得诊断具有挑战性。然而，对于有症状的病例，在出生后第一个月内进行药物治疗的早期诊断至关重要。高胆红素血症和脾肿大在出生时是较不常见的表现，在有其他症状的情况下可能会被忽视，尤其是在危重新生儿中。我们报告一例患有21三体综合征的足月儿，该患儿仅表现为高胆红素血症和脾肿大，后来被诊断为先天性巨细胞病毒感染。
