Department of Spinal Surgery, Peking University People's Hospital, Peking University, No. 11 Xizhimen South Street, 100044, Xicheng District, Beijing, People's Republic of China.
J Orthop Surg Res. 2020 Feb 26;15(1):79. doi: 10.1186/s13018-020-01589-7.
To compare sagittal alignment and clinical outcomes between three-level hybrid surgery (HS) and anterior cervical discectomy and fusion (ACDF) on cervical spondylotic myelopathy (CSM) over a 5-year follow-up.
The study included 32 patients with ACDF, 36 patients with 1 prosthesis and 2 cages (HS1 group), and 25 cases with 2 prostheses and 1 cage (HS2 group). Alignment parameters included C2-C7 cervical lordosis (CL), C2-C7 sagittal vertical axis (SVA), T1 slope (T1S), and T1S minus CL (T1SCL). Radiographic parameters were range of motion (ROM), upper and lower adjacent ROM (UROM and LROM), and operated-segment lordosis (OPCL), as well as adjacent segment degeneration (ASD). Clinical outcomes included the neck disability index (NDI) and Japanese Orthopedic Association (JOA) score.
Three groups were well-matched in demographics. All groups gained comparable improvement on NDI and JOA (P < 0.01). All groups gained CL improvement at the final visit (P < 0.05). There were no statistical differences on SVA and T1SCL among the groups and among preoperation, 1 week later, and final follow-up (P > 0.05) while T1S improved at 1 week later and final follow-up with HS2. The final change of all alignment parameters among the three groups was of no differences. ROM decreased and OPCL increased in all groups at the final follow-up (P < 0.05). UROM and LROM increased with ACDF but kept stable with HS1 and HS2. There was no inter-group difference on the incidence of ASD (P > 0.05).
Cervical alignment was comparably improved. HS and ACDF provided identified mid-term efficacy, and it was not necessary to have to use prosthesis on three-level CSM.
比较三平面融合手术(HS)与前路颈椎间盘切除融合术(ACDF)治疗颈椎病脊髓病(CSM)的矢状面排列和临床结果,随访时间为 5 年。
本研究纳入了 32 例行 ACDF 的患者、36 例行 1 个假体和 2 个椎间融合器(HS1 组)和 25 例行 2 个假体和 1 个椎间融合器(HS2 组)的患者。矢状面参数包括 C2-C7 颈椎前凸(CL)、C2-C7 矢状垂直轴(SVA)、T1 斜坡(T1S)和 T1S 减去 CL(T1SCL)。影像学参数包括活动度(ROM)、上下相邻节段活动度(UROM 和 LROM)和手术节段前凸(OPCL),以及相邻节段退变(ASD)。临床结果包括颈部残疾指数(NDI)和日本矫形协会(JOA)评分。
三组在人口统计学上匹配良好。所有组在 NDI 和 JOA 方面均获得相当程度的改善(P<0.01)。所有组在最终随访时均获得 CL 的改善(P<0.05)。三组间在 SVA 和 T1SCL 方面无统计学差异,在术前、术后 1 周和最终随访时也无统计学差异(P>0.05),而 T1S 在术后 1 周和最终随访时在 HS2 组中有所改善。三组间所有排列参数的最终变化无差异。所有组在最终随访时 ROM 减小,OPCL 增加(P<0.05)。UROM 和 LROM 在 ACDF 中增加,但在 HS1 和 HS2 中保持稳定。三组间 ASD 的发生率无差异(P>0.05)。
颈椎排列得到了相似的改善。HS 和 ACDF 提供了确定的中期疗效,对于 3 节段 CSM,没有必要使用假体。