From the Division of Experimental Medicine and Immunotherapeutics, University of Cambridge, Addenbrooke's Hospital, United Kingdom (I.B.W., K.M.M.-P.).
Cardiovascular Engineering, Inc, Norwood, MA (G.F.M.).
Arterioscler Thromb Vasc Biol. 2020 May;40(5):1063-1067. doi: 10.1161/ATVBAHA.120.313130. Epub 2020 Feb 27.
As far back as the ancient Egyptians and Greeks, physicians have observed and interpreted the arterial pulse to diagnose disease. In the last 20 years, advances in modern engineering have rendered quantitative pulse wave analysis widely available, reliable, and reproducible. To date, measurement of arterial stiffness has remained almost exclusively a research activity. However, ongoing technological improvements coupled with already strong and growing evidence of clinical value should facilitate integration of arterial stiffness measures into clinical practice in the near future. This brief review will highlight clinical areas where arterial stiffness measures are likely to be the most informative in clinical practice.
早在古埃及和古希腊时期,医生就已经观察和解释动脉脉搏以诊断疾病。在过去的 20 年中,现代工程学的进步使得定量脉搏波分析广泛可用、可靠且可重复。迄今为止,动脉僵硬度的测量几乎仍然是一项研究活动。然而,正在进行的技术改进以及已经非常强大且不断增长的临床价值证据应该有助于在不久的将来将动脉僵硬度测量纳入临床实践。这篇简短的综述将重点介绍动脉僵硬度测量在临床实践中最有可能提供信息的临床领域。