Department of Breast Surgery, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, China.
Department of Urology, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, China.
Biomed Res Int. 2020 Feb 13;2020:9082924. doi: 10.1155/2020/9082924. eCollection 2020.
This meta-analysis was conducted to compare the complication rates between arm and chest ports in patients with breast cancer. . PubMed, Embase, Cochrane library, Chinese National Knowledge Infrastructure (CNKI), and Wanfang database were used to perform a systematic review and meta-analysis of publications published from the inception of the database to 11, October 2019. Our search generated a total of 22 articles published from 2011 to 2019, including 6 comparative studies and 16 single-arm articles, involving 4131 cases and 5272 controls. Single-arm studies combined with comparative studies were also pooled and analyzed. Finally, subgroup analysis was performed to compare the rates of infection and thrombosis between these two ports. . Included articles were research studies comparing complication rates of arm ports with chest ports in patients with breast cancer. Any review or meta-analysis article would be removed. . Demographic data and information for the following analysis were extracted. DerSimonian and Laird random effect meta-analysis was conducted to analyze comparative studies while Begg's and Egger's tests were used for assessment of publication bias. Meta-regression analysis was performed to explain the sources of heterogeneity.
There was no difference in the risk of overall complications between arm and chest ports for comparative studies (=0.083). While results of pooled comparative and single-arm studies indicated that arm port would increase the overall complication risks with of 2.64, results of the subgroup analysis showed that there was no difference in the risk of catheter-related infection between these two ports. However, arm port might be associated with the higher thrombosis rates compared with chest port according to the results of the analysis for only comparative studies ( of 2.64, results of the subgroup analysis showed that there was no difference in the risk of catheter-related infection between these two ports. However, arm port might be associated with the higher thrombosis rates compared with chest port according to the results of the analysis for only comparative studies (=0.083). While results of pooled comparative and single-arm studies indicated that arm port would increase the overall complication risks with of 2.64, results of the subgroup analysis showed that there was no difference in the risk of catheter-related infection between these two ports. However, arm port might be associated with the higher thrombosis rates compared with chest port according to the results of the analysis for only comparative studies (=0.083). While results of pooled comparative and single-arm studies indicated that arm port would increase the overall complication risks with.
This study indicated that the arm port might increase the risk of overall complication risks as well as the risk of catheter-related thrombosis compared with the chest port. However, these reported findings still need to be verified by large randomized clinical trials.
本荟萃分析旨在比较乳腺癌患者使用手臂港和胸港的并发症发生率。我们检索了从数据库建立到 2019 年 10 月 11 日发表的文献，使用 PubMed、Embase、Cochrane 图书馆、中国知网（CNKI）和万方数据库进行系统评价和荟萃分析。我们的检索共生成了 2011 年至 2019 年发表的 22 篇文章，包括 6 项对照研究和 16 项单臂研究，涉及 4131 例和 5272 例对照。单臂研究与对照研究相结合也进行了汇总分析。最后，进行了亚组分析以比较这两种港口的感染和血栓形成率。纳入的文章是比较乳腺癌患者使用手臂港和胸港并发症发生率的研究。将删除任何综述或荟萃分析文章。提取人口统计学数据和以下分析信息。使用 DerSimonian 和 Laird 随机效应荟萃分析对对照研究进行分析，使用 Begg 和 Egger 检验评估发表偏倚。进行了元回归分析以解释异质性的来源。结果：对于对照研究，手臂港与胸港的总体并发症风险无差异（=0.083）。汇总对照和单臂研究的结果表明，手臂港会增加总体并发症风险，比值比（OR）为 2.64，亚组分析的结果表明，这两种港口的导管相关感染风险无差异。然而，根据仅针对对照研究的分析结果，手臂港与胸港相比可能与更高的血栓形成率相关（OR=2.64，亚组分析的结果表明，这两种港口的导管相关感染风险无差异。然而，根据仅针对对照研究的分析结果，手臂港与胸港相比可能与更高的血栓形成率相关（OR=2.64，亚组分析的结果表明，这两种港口的导管相关感染风险无差异。然而，根据仅针对对照研究的分析结果，手臂港与胸港相比可能与更高的血栓形成率相关（OR=2.64，亚组分析的结果表明，这两种港口的导管相关感染风险无差异。然而，根据仅针对对照研究的分析结果，手臂港与胸港相比可能与更高的血栓形成率相关（OR
