针对[具体物种1]和[具体物种2]的化学成分及抗真菌活性。 （注：原文中against后面缺少具体物种信息，翻译时按此格式呈现，实际应用中应补充完整）
Chemical compositions and antifungal activities of against and species.
作者信息
Motamedi Marjan, Saharkhiz Mohammad Jamal, Pakshir Keyvan, Amini Akbarabadi Sara, Alikhani Khordshami Marzieh, Asadian Fatemeh, Zareshahrabadi Zahra, Zomorodian Kamiar
机构信息
Department of Medical Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Department of Horticultural Sciences, Faculty of Agriculture, Shiraz University, Shiraz, Iran.
出版信息
Curr Med Mycol. 2019;5(4):20-25. doi: 10.18502/cmm.5.4.2162.
BACKGROUND AND PURPOSE
Despite the various applications of species, there are limited data in this domain. Regarding this, the present study was conducted to investigate the essential oil (EO) biological activity of species in Iran.
MATERIALS AND METHODS
The EO of flowers was obtained by hydrodistillation. Chemical compositions of the EO were analyzed using gas chromatography-mass spectrometry. In addition, minimum inhibitory concentrations (MIC) were measured by means of the broth microdilution method. The estimation of antibiofilm and cytotoxic activities was also accomplished using the tetrazolium salt and MTT assays, respectively.
RESULTS
A total of 26 components were identified in the EO with linalool as the main constituent (28.46%). A MIC range value of 0.25-8 μL/mL was obtained against all of the tested fungi. The EO inhibited the biofilm development of the tested strains at a concentration of 4-8 μL/mL. Cytotoxicity (IC) of EO against the HeLa cell was greater than the MIC concentration (6.49 μL/mL).
CONCLUSION
Based on the findings, it was concluded that the EO of has the potential for further use as an antifungal agent.
背景与目的
尽管该物种有多种应用，但该领域的数据有限。鉴于此，本研究旨在调查伊朗该物种的精油（EO）生物活性。
材料与方法
通过水蒸馏法获得该花的精油。采用气相色谱 - 质谱联用仪分析精油的化学成分。此外，通过肉汤微量稀释法测定最低抑菌浓度（MIC）。还分别使用四氮唑盐和MTT法评估抗生物膜和细胞毒性活性。
结果
在精油中总共鉴定出26种成分，其中芳樟醇为主要成分（28.46%）。对所有测试真菌的MIC范围值为0.25 - 8 μL/mL。该精油在浓度为4 - 8 μL/mL时抑制了测试菌株的生物膜形成。精油对HeLa细胞的细胞毒性（IC）大于MIC浓度（6.49 μL/mL）。
结论
基于这些发现，得出该物种的精油有进一步用作抗真菌剂的潜力的结论。
Zotero 插件