Giwa Al, Desai Akash
Associate Professor of Emergency Medicine, Icahn School of Medicine at Mount Sinai, New York, NY
Icahn School of Medicine at Mount Sinai, New York, NY
Emerg Med Pract. 2020 Feb 27;22(2 Suppl 2):1-21.
Prior to the global outbreak of SARS-CoV in 2003, HCoV-229E and HCoV-OC43 were the only coronaviruses known to infect humans. Following the SARS outbreak, 5 additional coronaviruses have been discovered in humans, most recently the novel coronavirus COVID-19, believed to have originated in Wuhan, Hubei Province, China. SARS-CoV and MERSCoV are particularly pathogenic in humans and are associated with high mortality. In this review, the epidemiology, pathophysiology, and management of the recently discovered COVID-19 are reviewed, with a focus on best practices and the public health implications.
在2003年严重急性呼吸综合征冠状病毒(SARS-CoV)全球爆发之前,HCoV-229E和HCoV-OC43是已知的仅有的两种可感染人类的冠状病毒。SARS爆发后,又在人类中发现了另外5种冠状病毒,最近的一种是新型冠状病毒COVID-19,据信起源于中国湖北省武汉市。SARS-CoV和中东呼吸综合征冠状病毒(MERSCoV)对人类具有特别强的致病性,并与高死亡率相关。在这篇综述中,我们对最近发现的COVID-19的流行病学、病理生理学及管理进行了综述,重点关注最佳实践及对公共卫生的影响。