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超重、肥胖与韩国成年人发生重度龋齿的相关性:一项为期 10 年的全国范围内基于人群的观察性研究。

Association between overweight, obesity and incidence of advanced dental caries in South Korean adults: A 10-year nationwide population-based observational study.

机构信息

Department of Conservative Dentistry, College of Medicine, Seoul St. Mary's Dental Hospital, The Catholic University of Korea, Seoul, Korea.

Department of Biostatistics, College of Medicine, The Catholic University of Korea, Seoul, Korea.

出版信息

PLoS One. 2020 Feb 27;15(2):e0229572. doi: 10.1371/journal.pone.0229572. eCollection 2020.

DOI:10.1371/journal.pone.0229572
PMID:32107502
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7046206/
Abstract

The objective of this study was to evaluate the association between overweight, obesity and the incidence of advanced dental caries in South Korean adults, using alternate measures. The participants included 376,077 people aged 20 years and older who had health examination at least one time between 2005 and 2008. This evaluation is based on a change of body mass index (BMI) category, for 10 years, using a nationally representative data resource available from the National Health Insurance System. Instead of using decayed, missing, and filled teeth (DMFT), the diagnostic codes which indicate dental caries, pulpal disease and visiting frequency at dental health professionals were used in this case. A multivariate adjusted Cox regression analysis was performed to examine the association between advanced dental caries and BMI. In addition to the BMI, a multivariate analysis of gender, age, lifestyle behaviors and systemic disease information was included. To this end, the hazard ratio (HR) and 95% confidence interval (CI) were calculated. Chiefly, it is noted that the overweight and obese people were more likely to develop advanced dental caries independent of the noted variables. The positive association between high BMI and incidence of advanced dental caries was more prominent in the population's characteristic of people who were in a classification of the elderly and women. Among the health and lifecycle behaviors, smoking or not was found to be one of the factors affecting the results. The alternate method used in this study showed that being overweight and obesity had a direct association with the incidence of advanced dental caries in Korean adults.

摘要

本研究旨在评估超重和肥胖与韩国成年人中严重龋齿发病之间的关联,采用替代指标。参与者包括 376077 名年龄在 20 岁及以上的人群,他们在 2005 年至 2008 年间至少进行过一次健康检查。这一评估是基于 10 年内身体质量指数(BMI)类别变化的情况,使用的是国家健康保险系统提供的全国代表性数据资源。在这种情况下,使用的是诊断龋齿、牙髓疾病和口腔卫生专业人员就诊频率的代码,而不是使用龋失补牙数(DMFT)。采用多变量调整 Cox 回归分析来检验严重龋齿与 BMI 之间的关联。除了 BMI 之外,还对性别、年龄、生活方式行为和系统性疾病信息进行了多变量分析。为此,计算了危害比(HR)和 95%置信区间(CI)。主要注意到,超重和肥胖人群发生严重龋齿的可能性独立于上述变量更高。高 BMI 与严重龋齿发病之间的正相关在年龄较大和女性人群中的特征更为明显。在健康和生命周期行为方面,吸烟与否是影响结果的因素之一。本研究中采用的替代方法表明,超重和肥胖与韩国成年人严重龋齿的发生有直接关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77a4/7046206/034ffc893318/pone.0229572.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77a4/7046206/5c2749639806/pone.0229572.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77a4/7046206/034ffc893318/pone.0229572.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77a4/7046206/5c2749639806/pone.0229572.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77a4/7046206/034ffc893318/pone.0229572.g002.jpg

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