氟代隐色 cryptophane-A 和基于卟啉的诊疗一体试剂用于多模态成像引导的光动力治疗。
Fluorinated cryptophane-A and porphyrin-based theranostics for multimodal imaging-guided photodynamic therapy.
机构信息
Hubei Province Engineering and Technology Research Center for Fluorinated Pharmaceuticals and School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China.
出版信息
Chem Commun (Camb). 2020 Mar 28;56(25):3617-3620. doi: 10.1039/d0cc00694g. Epub 2020 Feb 28.
PMID:32108215
Abstract
Herein, we developed fluorinated nanoemulsions with significantly enhanced in vitro and in vivoXe hyper-CEST MRI, F MRI and fluorescence imaging signals for selective and sensitive tumor detection and NIR-activated photodynamic therapy.
摘要
在此，我们开发了具有显著增强的体外和体内 Xe 超 CEST MRI、F MRI 和荧光成像信号的氟纳米乳液，用于选择性和灵敏的肿瘤检测和近红外激活光动力治疗。
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