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混合性焦虑抑郁障碍治疗中的多学科干预。

Multidisciplinary intervention in the treatment of mixed anxiety and depression disorder.

作者信息

Clemente-Suárez Vicente Javier

机构信息

Universidad Europea de Madrid, Faculty of Sport Sciences; Grupo de Investigación en Cultura, Educación y Sociedad, Universidad de la Costa, Barranquilla, Colombia.

出版信息

Physiol Behav. 2020 May 15;219:112858. doi: 10.1016/j.physbeh.2020.112858. Epub 2020 Feb 26.

DOI:10.1016/j.physbeh.2020.112858
PMID:32109486
Abstract

Depression and anxiety disorders are one of the main limiting psychopathologies in the world today. This pathology is linked to an inflammatory state and a dysregulation of both neurotransmitters and autonomic nervous system. Various treatments from psychiatric and psychological areas have shown different degrees of efficacy in their treatment, being Cognitive Behavioral Therapy one of the most successful. In addition, various interventions from other areas of knowledge are showing significant improvements in this pathology. This research aimed to analyze the psychological and physiological modifications of a multidisciplinary intervention that combines psychological treatment (Cognitive Behavioral Therapy), physical activity and nutritional intervention in a mixed anxiety and depression disorder (DSM-V). We analyzed modifications in the HAM-D depression, STAI anxiety questionnaire, subjective perceptions of anxiety, happiness, sleep and motivation and the autonomous modulation before and after a 6 multidisciplinary sessions of cognitive behavioral therapy, aerobic physical activity and nutritional intervention in a subject with a mixed anxiety and depression disorder. The results showed a reduction in the values of depression in HAM-D until the classification of non-depression, a reduction in both state and trait anxiety, an increase in the subjective perceptions of sleep, happiness and motivation and a greater parasympathetic modulation after the six intervention sessions. The combination of psychological therapy with aerobic physical activity and nutritional recommendations to treat mixed anxiety and depression disorder produced an increased parasympathetic tone and a decreased anxiety and depression symptoms in six sessions. This is a novel research that allows us to open the study of a new multidisciplinary field in the treatment of this disease that is highly present today.

摘要

抑郁症和焦虑症是当今世界主要的限制性精神病理学疾病之一。这种病理学与炎症状态以及神经递质和自主神经系统的失调有关。来自精神病学和心理学领域的各种治疗方法在其治疗中显示出不同程度的疗效,认知行为疗法是最成功的方法之一。此外,来自其他知识领域的各种干预措施在这种病理学方面也显示出显著改善。本研究旨在分析一种多学科干预措施的心理和生理变化,该干预措施结合了心理治疗(认知行为疗法)、体育活动和营养干预,用于治疗混合性焦虑和抑郁症(DSM-V)。我们分析了一名患有混合性焦虑和抑郁症的受试者在接受6次认知行为疗法、有氧体育活动和营养干预的多学科治疗前后,汉密尔顿抑郁量表(HAM-D)、状态-特质焦虑量表(STAI)、焦虑的主观感受、幸福感、睡眠和动机以及自主调节方面的变化。结果显示,HAM-D抑郁值降低至非抑郁分类,状态焦虑和特质焦虑均降低,睡眠、幸福感和动机的主观感受增加,并且在6次干预疗程后副交感神经调节增强。心理治疗与有氧体育活动及营养建议相结合来治疗混合性焦虑和抑郁症,在6个疗程中产生了副交感神经张力增加以及焦虑和抑郁症状减轻的效果。这是一项新颖的研究,使我们能够开启对治疗这种当今普遍存在疾病的新多学科领域的研究。

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