Taş Halil İbrahim, Altinbaş Kürşat
Department of Psychiatry, Çanakkale Onsekiz Mart University School of Medicine, Çanakkale, Turkey.
Department of Psychiatry, Selçuk University School of Medicine, Konya, Turkey.
Noro Psikiyatr Ars. 2019 Sep 12;57(1):27-32. doi: 10.29399/npa.23610. eCollection 2020 Mar.
"Depressive disorder with mixed features" has been included in the official classification in the latest version of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). Hypothesizing that difficulties in emotion regulation and affective temperament scores are higher in mixed depression comparing to pure depression, we aimed to evaluate the relationship between these phenomena and mixed symptoms.
Depressive patients diagnosed by a psychiatrist according to the DSM-5 and had not received any psychiatric treatment for the last 3 months, were included in the study. The Hamilton Rating Scale (HDRS), modified Hypomania Checklist (mHCL), Difficulties in Emotion Regulation Scale (DERS), and the TEMPS-A (Temperament Evaluation of Memphis, Pisa, Paris, San Diego Autoquestionaire) were applied to all participants.
Of the 63 participants, 40 (63.5%) were women. The mean age was 37.8±12.4 years while mean duration of education was 10.8±4.3 years. The proportion of mixed-depression assessed by the mHCL was 23.8% (n=15). No significant difference was found between the groups concerning gender, age, family history, age at onset of illness, the total number of episodes and temperament scores. Depressive patients with mixed features had significantly higher DERS nonacceptance subscale scores. Multiple regression analysis demonstrated that the cyclothymic temperament scale scores significantly affected the total mHCL scores.
In mixed depression group, higher scores in nonacceptance subscale seems to reflect a tendency to fluctuations in the emotional reactions of a person to the stress. Association between mixed depression, DERS nonacceptance subscale and cyclothymic temperament support the spectrum view that mixed depression is placed between pure depression and bipolarity.
“伴有混合特征的抑郁障碍”已被纳入最新版《精神疾病诊断与统计手册》（DSM - 5）的官方分类中。鉴于假设混合性抑郁症患者在情绪调节方面存在困难且情感气质得分高于单纯抑郁症患者，我们旨在评估这些现象与混合症状之间的关系。
纳入由精神科医生根据DSM - 5诊断的抑郁症患者，且在过去3个月内未接受任何精神科治疗。对所有参与者应用汉密尔顿评定量表（HDRS）、改良轻躁狂检查表（mHCL）、情绪调节困难量表（DERS）和TEMPS - A（孟菲斯、比萨、巴黎、圣地亚哥气质自评量表）。
63名参与者中，40名（63.5%）为女性。平均年龄为37.8±12.4岁，平均受教育年限为10.8±4.3年。经mHCL评估的混合性抑郁症比例为23.8%（n = 15）。两组在性别、年龄、家族史、发病年龄、发作总数和气质得分方面未发现显著差异。伴有混合特征的抑郁症患者的DERS不接受分量表得分显著更高
