丁香酚在叶提取物中的抗氧化活性。
Antioxidant activity of eugenol in leaf extract.
作者信息
Aara Anjum, Chappidi Vani, Ramadas Madhavan N
机构信息
Department Oral and Maxillofacial Pathology, Faculty of Dentistry, Annamalai University, Chidambaram, Tamil Nadu, India.
Department of Oral Medicine and Radiology, Sri Sai College of Dental Surgery, Vikarabad, Telangana, India.
出版信息
J Family Med Prim Care. 2020 Jan 28;9(1):327-331. doi: 10.4103/jfmpc.jfmpc_809_19. eCollection 2020 Jan.
BACKGROUND
Extracts of Piper betel are used for the treatment of various ailments since ages due to its essential properties like antioxidant, anticancer, anti-allergic etc. In the present study antioxidant activity for Piper betel leaf extract and Eugenol was assessed. Eugenol was taken as marker compound.
METHODS
Nitric oxide, Hydroxyl radical and Reducing power assay methods were carried out for assessment of antioxidant activity of Piper betel.
RESULTS
The antioxidant activity for Nitric oxide, Hydroxyl radical and Reducing power assay at 1000 to 62.5μg/ml was performed. The antioxidant activity of Piper betel leaf extract exhibited the IC50 value for Nitric oxide and Hydroxyl radical >1000 whereas Eugenol exhibited the IC50 value 114.34± 0.46 and 306.44 ± 5.28 respectively, for reducing power assay (RPA) Piper betel leaf extract and Eugenol revealed the RPA value ranging from 0.44-0.08 and 0.53-0.12.
CONCLUSION
The benefits of Piper betel have been mentioned in our ancient texts. Keeping in view the emergence of various diseases and the benefits of Piper betei, there is need that every effort should be made to revive this treasure of nature into our daily supplement.
背景
由于具有抗氧化、抗癌、抗过敏等基本特性，蒌叶提取物长期以来一直用于治疗各种疾病。在本研究中，对蒌叶提取物和丁香酚的抗氧化活性进行了评估。丁香酚被用作标记化合物。
方法
采用一氧化氮、羟自由基和还原力测定方法评估蒌叶的抗氧化活性。
结果
在1000至62.5μg/ml浓度下进行了一氧化氮、羟自由基和还原力测定的抗氧化活性实验。蒌叶提取物对一氧化氮和羟自由基的抗氧化活性表现出IC50值>1000，而丁香酚对还原力测定（RPA）的IC50值分别为114.34±0.46和306.44±5.28。对于RPA，蒌叶提取物和丁香酚的RPA值范围分别为0.44 - 0.08和0.53 - 0.12。
结论
我们的古代文献中已提及蒌叶的益处。鉴于各种疾病的出现以及蒌叶的益处，有必要尽一切努力将这种大自然的瑰宝重新纳入我们的日常补充剂中。
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