CAS Key Laboratory of Biogeography and Bioresource in Arid Land, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi, 830011, P. R. China.
Ministry of Education Key Laboratory of Xinjiang Phytomedicine Resource Utilization, College of Life Sciences, Shihezi University, Shihezi, 832003, P. R. China.
Chem Biodivers. 2020 Apr;17(4):e2000043. doi: 10.1002/cbdv.202000043. Epub 2020 Mar 18.
Alternariol and altenuisol were isolated as the major phytotoxins produced by an Alternaria sp. pathogenic fungus of the invasive weed Xanthium italicum. Altenuisol exhibited stronger phytotoxic effect compared with alternariol. At 10 μg/mL, alternariol and altenuisol promoted root growth of the monocot plant Pennisetum alopecuroides by 11.1 % and 75.2 %, respectively, however, inhibitory activity was triggered by the increase of concentration, with root elongation being suppressed by 35.5 % and 52.0 % with alternariol and altenuisol at 1000 μg/mL, respectively. Alternariol slightly inhibited root length of the dicot plant Medicago sativa at 10-1000 μg/mL, whereas altenuisol stimulated root growth by 51.0 % at 10 μg/mL and inhibited root length by 43.4 % at 200 μg/mL. Alternariol and altenuisol did not exert strong regulatory activity on another dicot plant, Amaranthus retroflexus, when tested concentration was low, however, when the concentration reached 1000 μg/mL, they reduced root length by 68.1 % and 51.0 %, respectively. Alternariol and altenuisol exerted similar effect on shoot growth of three tested plants but to a lesser extent. It is noteworthy to mention that this is the first report on the phytotoxicity of altenuisol.
交替单端孢霉醇和交替单端孢烯醇被鉴定为一种对入侵杂草豚草具有致病性的链格孢真菌的主要植物毒素。与交替单端孢霉醇相比，交替单端孢烯醇表现出更强的植物毒性作用。在 10μg/mL 时，交替单端孢霉醇和交替单端孢烯醇分别促进了单子叶植物狗尾草根系生长 11.1%和 75.2%，然而，随着浓度的增加，抑制活性被触发，当浓度分别为 1000μg/mL 时，狗尾草的根系伸长率分别受到 35.5%和 52.0%的抑制。在 10-1000μg/mL 时，交替单端孢霉醇对双子叶植物紫花苜蓿的根长略有抑制，而在 10μg/mL 时，交替单端孢烯醇刺激根生长 51.0%，在 200μg/mL 时抑制根长 43.4%。在低浓度时，交替单端孢霉醇和交替单端孢烯醇对另一种双子叶植物反枝苋没有很强的调节作用，但当浓度达到 1000μg/mL 时，它们分别使根长减少了 68.1%和 51.0%。交替单端孢霉醇和交替单端孢烯醇对三种测试植物的茎生长产生相似的影响，但程度较小。值得注意的是，这是首次报道交替单端孢烯醇的植物毒性。
