葡萄籽原花青素提取物对肥胖的影响。
Effects of Grape Seed Proanthocyanidin Extract on Obesity.
作者信息
Liu Miao, Yun Peng, Hu Ying, Yang Jiao, Khadka Rim Bahadur, Peng Xiaochun
机构信息
Medical School of Yangtze University, Jingzhou, China.
Department of Endocrinology, the Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, China.
出版信息
Obes Facts. 2020;13(2):279-291. doi: 10.1159/000502235. Epub 2020 Feb 28.
Abstract
Obesity is a chronic metabolic disease resulting from excessive fat accumulation and/or abnormal distribution caused by multiple factors. As a major component of metabolic syndrome, obesity is closely related to many diseases such as type 2 diabetes mellitus, hyperlipidemia, hypertension, coronary heart disease, stroke and cancer. Hence, the problem of obesity cannot be ignored, and recent studies have shown that grape seed proanthocyanidin extract (GSPE) has an antiobesity effect. This paper systematically reviews the research progress and potential mechanism of GSPE emphasizing on obesity prevention and treatment.
摘要
肥胖是一种慢性代谢性疾病，由多种因素导致的脂肪过度堆积和/或分布异常引起。作为代谢综合征的主要组成部分，肥胖与许多疾病密切相关，如2型糖尿病、高脂血症、高血压、冠心病、中风和癌症。因此，肥胖问题不容忽视，最近的研究表明葡萄籽原花青素提取物（GSPE）具有抗肥胖作用。本文系统综述了GSPE在肥胖预防和治疗方面的研究进展及潜在机制。
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