Shen Biyu, Li Yongchang, Du Xian, Chen Haoyang, Xu Yucheng, Li Huiling, Xu Guang-Yin
Center for Translational Pain Medicine, Institute of Neuroscience, Soochow University , Suzhou, China.
Nursing School of Soochow University, Soochow University , Suzhou, China.
Psychol Health Med. 2020 Dec;25(10):1179-1191. doi: 10.1080/13548506.2020.1736312. Epub 2020 Mar 4.
This study aimed to assess the effects of cognitive behavioral therapy on the psychological and physiological health of rheumatoid arthritis patients. An extensive literature search was conducted, using the PubMed, Web of Science, Cochrane Library, Embase, CNKI Scholar, WanFang, and VIP databases, from inception to December2018. The quality of the studies was evaluated by 2 independent authors, according to the basic criteria provided by the Cochrane Handbook for evaluating randomized trials. Meta-analysis was performed with Review Manager 5.3. Six randomized controlled trials met the inclusion criteria of the current study. Using standard mean differences (SMD) and 95% confidence intervals (CI), our results showed that cognitive behavioral therapy could significantly reduce levels of anxiety (SMD = -0.30, 95% CI [-0.52, -0.09], P= 0.005) and depression (SMD = -0.48, 95% CI [-0.70, -0.27], P< 0.00001), and relieve fatigue symptoms (SMD = -0.35, 95% CI [-0.60, -0.10], P= 0.006) in rheumatoid arthritis patients.This is the first known assessment of the efficacy of cognitive behavioral therapy on rheumatoid arthritis patients using meta-analysis. Large-scale randomized controlled trials need to be implemented to further explore this issue.
本研究旨在评估认知行为疗法对类风湿性关节炎患者心理和生理健康的影响。我们使用PubMed、科学网、考克兰图书馆、Embase、中国知网、万方和维普数据库，进行了一项从建库至2018年12月的广泛文献检索。由2位独立作者根据考克兰系统评价干预措施手册中提供的评估随机试验的基本标准对研究质量进行评估。使用Review Manager 5.3进行荟萃分析。六项随机对照试验符合本研究的纳入标准。采用标准化均数差（SMD）和95%置信区间（CI），我们的结果显示，认知行为疗法可显著降低类风湿性关节炎患者的焦虑水平（SMD = -0.30，95%CI [-0.52, -0.09]，P = 0.005）和抑郁水平（SMD = -0.48，95%CI [-0.70, -0.27]，P < 0.00001），并缓解疲劳症状（SMD = -0.35，95%CI [-0.60, -0.10]，P = 0.006）。这是首次使用荟萃分析评估认知行为疗法对类风湿性关节炎患者疗效的研究。需要开展大规模随机对照试验以进一步探究这一问题。
