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慢性颌面疼痛。

Chronic orofacial pain.

机构信息

Department of Diagnostic Sciences, Center for Temporomandibular Disorders and Orofacial Pain, Rutgers School of Dental Medicine, 110 Bergen Street, Newark, NJ, 07101, USA.

出版信息

J Neural Transm (Vienna). 2020 Apr;127(4):575-588. doi: 10.1007/s00702-020-02157-3. Epub 2020 Mar 4.

DOI:10.1007/s00702-020-02157-3
PMID:32130516
Abstract

While pain chronicity in general has been defined as pain lasting for more than 3 months, this definition is not useful in orofacial pain (OFP) and headache (HA). Instead, chronicity in OFP and HA is defined as pain occurring on more than 15 days per month and lasting for more than 4 h daily for at least the last 3 months. This definition excludes the periodic shortlasting pains that often recur in the face and head, but are not essentially chronic. Although the headache field has adopted this definition, chronic orofacial pain is still poorly defined. In this article, we discuss current thinking of chronicity in pain and examine the term 'chronic orofacial pain' (COFP). We discuss the entities that make up COFP and analyze the term's usefulness in clinical practice and epidemiology.

摘要

虽然一般来说,慢性疼痛被定义为持续超过 3 个月的疼痛,但这种定义在口腔颌面部疼痛(OFP)和头痛(HA)中并不适用。相反,OFP 和 HA 的慢性疼痛定义为每月疼痛发作超过 15 天,且持续至少 3 个月,每天疼痛持续时间超过 4 小时。这个定义排除了经常在面部和头部反复发作的短暂性疼痛,但它们并不是本质上的慢性疼痛。尽管头痛领域已经采用了这个定义,但慢性口腔颌面部疼痛的定义仍然不够完善。在本文中,我们讨论了疼痛慢性化的当前观点,并研究了“慢性口腔颌面部疼痛”(COFP)这个术语。我们讨论了构成 COFP 的实体,并分析了该术语在临床实践和流行病学中的有用性。

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Peripheral and Central Mechanisms of Persistent Orofacial Pain.持续性口面部疼痛的外周和中枢机制
Front Neurosci. 2019 Nov 13;13:1227. doi: 10.3389/fnins.2019.01227. eCollection 2019.
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Features of Neurovascular Orofacial Pain Compared to Painful Posttraumatic Trigeminal Neuropathy.神经血管性口面痛与创伤性三叉神经痛后痛的特征比较。
伴有中枢敏化的口面部慢性疼痛患者的脑功能连接和神经代谢物相关性改变
J Pain Res. 2025 Jun 9;18:2849-2863. doi: 10.2147/JPR.S507893. eCollection 2025.
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Comparative analysis of acute and chronic painful temporomandibular disorders: Insights into pain, behavioral, and psychosocial features.急性和慢性疼痛性颞下颌关节紊乱病的比较分析:对疼痛、行为及社会心理特征的见解
PLoS One. 2025 Feb 25;20(2):e0318946. doi: 10.1371/journal.pone.0318946. eCollection 2025.
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